JC Polyomavirus in Prostate Cancer—Friend or Foe? [PDF]
CancersBackground/Objectives: Recently, many researchers have evaluated various viruses, including polyomaviruses (JCV, BKV) and EBV, as potential factors playing a role in the development and/or progression of prostate cancer (PCa), one of the most common cancers in men.
Jacek Kiś +3 more
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JC Polyomavirus-Associated Nephropathy Case Report: Clinical and Laboratory Learning [PDF]
British Journal of Biomedical ScienceIntroductionJohn Cunningham (JC) virus is commonly associated with progressive multifocal leukoencephalopathy. However, this polyomavirus can also be a rare etiological agent of nephropathy in renal transplant recipients.
Rachael M. Tomb +5 more
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Neurovascular pericytes are susceptible to infection by JC polyomavirus [PDF]
Journal of VirologyABSTRACT Progressive multifocal leukoencephalopathy (PML), an often-fatal neurodegenerative disease, is caused by the neuroinvasive polyomavirus JCPyV. Peripheral organs, including the kidney, are the site of lifelong persistent infections that are asymptomatic. In a subset of immunosuppressed
Bethany A. O'Hara +4 more
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JC Polyomavirus, progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome: a review [PDF]
AIDS Research and Therapy, 2020 The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat +3 more
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JC Polyomavirus Nephropathy: A Rare Complication Late after Kidney Transplantation [PDF]
Case Reports in Nephrology and DialysisIntroduction: JC-polyomavirus-associated nephropathy (JC-PVAN) is a rare cause of allograft dysfunction with only a few cases described in the literature.
Jennifer Scotti Gerber +4 more
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GPCR Inhibitors Have Antiviral Properties against JC Polyomavirus Infection [PDF]
VirusesJC polyomavirus (JCPyV) infects the majority of the population and initially establishes a persistent but asymptomatic infection of the kidneys. In healthy individuals, the infection remains controlled by the host immune system, but for individuals ...
Amanda L. Sandberg +9 more
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Insights into the genetic characteristics, clustering patterns, and phylogeographic dynamics of the JC polyomavirus, 1993 to 2023 [PDF]
Virus ResearchThe human JC polyomavirus (JCV) is a widespread, neurotropic, opportunistic pathogen responsible for progressive multifocal leukoencephalopathy (PML) as well as other diseases in immunosuppressed individuals, including granule cell neuronopathy, JCV ...
Pir Tariq Shah +5 more
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Human polyomavirus JC virus genome [PDF]
Journal of Virology, 1984 The complete DNA sequence of the human JC virus, which was found to consist of 5,130 nucleotide pairs, is presented. The amino acid sequence of six proteins could be deduced: the early, nonstructural proteins, large T and small t antigens; the late capsid proteins, VP1, VP2, and VP3; and the agnogene product encoded within the late leader sequence ...
R J, Frisque, G L, Bream, M T, Cannella
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Phosphoinositide 3′-Kinase γ Facilitates Polyomavirus Infection
Viruses, 2020 Polyomaviruses are small, non-enveloped DNA tumor viruses that cause serious disease in immunosuppressed people, including progressive multifocal leukoencephalopathy (PML) in patients infected with JC polyomavirus, but the molecular events mediating ...
Paul Clark +6 more
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Polyomaviruses BK and JC DNA infection in peripheral blood cells from blood donors
Brazilian Journal of Infectious Diseases, 2019 Objectives: To investigate the prevalence of human polyomavirus (BK and JC viruses) infection in peripheral blood mononuclear cells of healthy blood donors. Methods: The study included 250 healthy blood donors.
Malihe Fathi Haghighi +7 more
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