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HIGH PREVALENCE OF JOHN CUNNINGHAM VIRURIA IN RENAL TRANSPLANT RECIPIENTS
Background: John Cunningham virus (JCV) is one of the important viruses in immunocompromised patients. High JC viruria is seen in kidney allograft recipients; some of them with a polyomavirus associated nephropathy (PVAN) just like BK polyomavirus but to
Mervit B. Jasim +4 more
doaj +6 more sources
BK (BKPyV) and JC (JCPyV) polyomaviruses are widespread in humans. Transmission at an early age and the role of parents in spreading these viruses through the family are incompletely understood.
Hanna K. Laine +5 more
doaj +1 more source
Prevalence of Human Polyomavirus JC and BK in Normal Population [PDF]
JC virus (JCV) , and BK virus (BKV) can remain latency in kidney and excrete via urine asymptomatically. JCV has been associated with colorectal and bladder cancers. BKV has been linked with lung, pancreas, liver, urogenital tract, head and neck cancers.
Karimi Dehcheshmeh, Lila +2 more
openaire +2 more sources
A Case of Primary JC Polyomavirus Infection–Associated Nephropathy [PDF]
A 15-year-old boy with a posterior urethral valve received a deceased donor kidney transplant (KT) in March 2011. Basiliximab induction followed by tacrolimus-based triple medication was used as immunosuppression. Eleven months after KT, the graft function deteriorated and the biopsy demonstrated interstitial nephritis suggestive of acute rejection. BK
Auvinen E. +11 more
openaire +4 more sources
Polyomavirus Wakes Up and Chooses Neurovirulence
JC polyomavirus (JCPyV) is a human-specific polyomavirus that establishes a silent lifelong infection in multiple peripheral organs, predominantly those of the urinary tract, of immunocompetent individuals.
Arrienne B. Butic +3 more
doaj +1 more source
JC Polyomavirus: Let's Please Respect Privacy [PDF]
ABSTRACT JC polyomavirus was discovered in 1971, and its name was derived from the initials of the individual from whose brain tissue it was isolated. While most scientists refer to the virus properly, i.e., calling it JCV or JCPyV, there is a small but palpable number of scientists who refer to the virus by the full name of the patient from ...
openaire +2 more sources
AIDS-related progressive multifocal leukoencephalopathy
INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV).
Carolina de Oliveira Abrão +5 more
doaj +1 more source
Potential Mechanisms of the Human Polyomavirus JC in Neural Oncogenesis [PDF]
The human polyomavirus JC (JCV) is a small DNA tumor virus and the etiologic agent of the progressive multifocal leukoencephalopathy. In progressive multifocal leukoencephalopathy, active JCV replication causes the lytic destruction of oligodendrocytes.
Luis, Del Valle +2 more
openaire +2 more sources
JC Virus and APOL1 Risk Alleles in Black South Africans With Hypertension-Attributed CKD
Introduction: The polyomaviruses, John Cunningham (JC) and BK, infect humans, with primary infection occurring in childhood. First-degree relatives of African American individuals with nondiabetic chronic kidney disease (CKD) who had 2 apolipoprotein L1 (
Nolubabalo U. Nqebelele +4 more
doaj +1 more source
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang +212 more
wiley +1 more source

