Results 171 to 180 of about 164,663 (253)

Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules

Plant Biotechnology Journal, EarlyView.
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan, Hiroko Miyadera, Kaho Oka, Kohei Ishikawa, Toshiya Kobayashi, Misaki Kobayashi, Mitsunori Shiroishi, Emiko Noguchi, Kenji Miura   +8 more
wiley   +1 more source

Pharmacologic Inhibition of JAK1/2 Potentiates Aminoglycoside-Induced Ototoxicity. [PDF]

Otol Neurotol
Fleegel J, Ezzat I, Vijayakumar S, Zallocchi M, Zuo J.   +4 more
europepmc   +1 more source

A TAF10‐ERF109 Transcriptional Module Directs Flavonoid‐Based Stress Resilience and Yield Enhancement in Foxtail Millet and Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT To ensure sustainable agricultural production under escalating environmental constraints such as drought and salinity, innovative strategies are urgently needed. Here, we reveal in foxtail millet (Setaria italica) that transcription factors TAF10 and ERF109 form a functional complex which co‐activates the expression of key flavonoid ...
Meng Zhang, Kangwei Wang, Jiayin Fan, Yue Zheng, Qi Zhang, Haoyang Du, Shenghui Xiao, Jinguang Huang, Kang Yan, Shizhong Zhang, Qiang He, Guanqing Jia, Chengchao Zheng, Xianmin Diao, Guodong Yang, Changai Wu   +15 more
wiley   +1 more source

Gardnerella vaginalis Urinary Tract Infection in a Term Neonate With Enteroviral Meningitis. [PDF]

Cureus
Lee MY, Valdivia-Trujillo AG, Sanchez PJ.   +2 more
europepmc   +1 more source

Development of In Vitro and In Planta Strategies for Efficient Production of High‐Value Steviol Glycosides

Plant Biotechnology Journal, EarlyView.
ABSTRACT Steviol glycosides (SGs) are a group of sweet‐tasting diterpene glycosides found in Stevia rebaudiana. Production of high‐value SGs, Rebaudioside D (Reb D) and Reb M, is limited by inefficient conversion of Reb A to Reb D and stevioside to Reb E.
Sing Hui Leong, Benny Jian Rong Sng, Ian Kin Yuen Choi, In‐Cheol Jang   +3 more
wiley   +1 more source

Genetic Incorporation of Diverse Noncanonical Amino Acids for Histidine Substitution. [PDF]

J Am Chem Soc
Natter Perdiguero A, Fischer S, Lischke AR, Manser BP, Deliz Liang A.   +4 more
europepmc   +1 more source

A Fusion Between Common Bean Phaseolin and the N‐Terminal Domain of Maize 16 kDa Gamma Zein: Clues for Designing Nutritionally Improved Seed Storage Proteins

Plant Biotechnology Journal, EarlyView.
ABSTRACT Increasing the nutritional value of seed storage proteins (SSPs) has been largely hindered by limited knowledge of how the features of the various SSP domains determine high accumulation in protein storage vacuoles (PSV) or as endoplasmic reticulum (ER)‐located insoluble protein bodies (PB).
Emma Costa, Lucrezia Luciani, Mahsa Taghipour Rahimi, Alessandro Vitale, Emanuela Pedrazzini   +4 more
wiley   +1 more source

Occurrence of third-generation cephalosporin-resistant Escherichia coli in European hedgehogs (Erinaceus europaeus) from a wildlife rescue centre in Lombardy, Northern Italy. [PDF]

Vet Res Commun
Raineri S, Gazzola A, Dilio G, Ventura S, Maisano AM, Guarneri F, Formenti N, Alborali GL, Magistrali CF, Filipe J, Rapi MC, Grilli G.   +11 more
europepmc   +1 more source

RNA‐Guided Engineering of the Chloroplast Genome Enabled by Plastid‐Expressed Guide RNAs

Plant Biotechnology Journal, EarlyView.
ABSTRACT Our goal is to develop RNA‐guided engineering of the chloroplast genome using the CRISPR/Cas9 system. We designed chloroplast minigenes to obtain properly sized single guide RNAs (sgRNAs) in tobacco chloroplasts. The sgRNA 5′ end is defined by transcription from an rRNA operon promoter, and its 3′ end by processing a downstream tRNA (trnG) or ...
Malihe Mirzaee, Corinne Best, Evelyn V. Wachowski, Pal Maliga   +3 more
wiley   +1 more source

High-throughput analyses of a reconstituted diversity-generating retroelement identify intrinsic and extrinsic determinants of diversification. [PDF]

PLoS Genet
Unlu I, Smiley MK, Potapov V, Renoux-Martin Y, Sun ZY, Lim HC.   +5 more
europepmc   +1 more source