Results 131 to 140 of about 1,219,583 (164)

K_ATP Channel Prodrugs Reduce Inflammatory and Neuropathic Hypersensitivity, Morphine-Induced Hypersensitivity, and Precipitated Withdrawal in Mice. [PDF]

J Pharmacol Exp Ther, 2023
Doucette A, Johnson K, Hulke S, Mujteba S, Miller E, Meyer B, Dosa PI, Klein AH.   +7 more
europepmc   +1 more source

Bayliss-Starling Prize Lecture: K_ATP channel pathophysiology - a whole-body odyssey. [PDF]

J Physiol
Nichols CG.
europepmc   +1 more source

The dynamic interplay of PIP₂ and ATP in the regulation of the K_ATP channel. [PDF]

J Physiol, 2022
Pipatpolkai T, Usher SG, Vedovato N, Ashcroft FM, Stansfeld PJ.   +4 more
europepmc   +1 more source

The cardioprotective role of sirtuins is mediated in part by regulating K_ATP channel surface expression.

Am J Physiol Cell Physiol, 2023
Tuncay E, Gando I, Huo JY, Yepuri G, Samper N, Turan B, Yang HQ, Ramasamy R, Coetzee WA.   +8 more
europepmc   +1 more source

The surprising complexity of KATP channel biology and of genetic diseases. [PDF]

J Clin Invest, 2020
Zhao G, Kaplan A, Greiser M, Lederer WJ.
europepmc   +1 more source

Hypoglycemic conditions enhance neonatal β-cell glucose responsiveness via AMPK/mTOR-increased KATP channel density.

Endocrinology
Novichkova E, Dou H, Gupta N, Kotova P, Tolö J, Miranda C, Rorsman P, Helman A, Walker MD.   +8 more
europepmc   +1 more source

Tyrosine phosphorylation of Kir6.2 subunit negatively regulates cardiac K_ATP channel activity. [PDF]

Basic Res Cardiol
Zhi Y, Yang B, Huo J, Wang H, Yang B, Zhou YF, Xiao F, Yang HQ.   +7 more
europepmc   +1 more source

Targeting p66Shc to restore K_ATP channel and renal microvascular responses in a preclinical model of diabetic nephropathy. [PDF]

Front Physiol
Miller B, Imig J, Goorani S, Schupbach P, Hays F, Benbrook DM, Sorokin A.   +6 more
europepmc   +1 more source

KATP channel expression and genetic polymorphisms associated with progression and survival in amyotrophic lateral sclerosis.

The ATP-sensitive potassium (KATP) channel directly regulates the microglia-mediated inflammatory response following CNS injury. To determine the putative role of the KATP channel in amyotrophic lateral sclerosis (ALS) pathology, we investigated whether ...
Vidal Taboada, José Manuel, Pugliese, Marco, Rodríguez Allué, Manuel José, Gamez, Josep, Mahy Gehenne, Josette Nicole, Salvado, Maria   +5 more
core  

K_ATP channel inhibition-induced hyporemia in skeletal muscle: No evidence for pre-capillary sphincter action. [PDF]

Microvasc Res
Schulze KM, Hirai DM, Colburn TD, Craig JC, Musch TI, Poole DC.   +5 more
europepmc   +1 more source