Results 191 to 200 of about 56,140 (348)

New Insights on Heat Shock Proteins as Regulators of Reactive Oxygen Species Across Various Stressors in Diseases

open access: yesCell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar   +5 more
wiley   +1 more source

Polydatin Protects Against the Formation of PPE‐Induced Abdominal Aortic Aneurysms in Mice by Activating Nuclear Factor Erythroid 2‐Related Factor 2

open access: yesDrug Development Research, Volume 87, Issue 1, February 2026.
ABSTRACT Sudden death resulting from abdominal aortic aneurysm (AAA) rupture is a highly fatal cardiovascular condition. There remains an urgent need to identify innovative therapeutic strategies capable of decelerating AAA progression and rupture. Although polydatin (PLD) has been consistently shown to exert potent anti‐inflammatory effects in diverse
Zikang Liu   +4 more
wiley   +1 more source

Targeting aerobic glycolysis combats tyrosine kinase inhibitor resistance of hepatocellular carcinoma

open access: yesInternational Journal of Cancer, Volume 158, Issue 3, Page 475-487, 1 February 2026.
Abstract Hepatocellular carcinoma (HCC) represents the predominant form of primary liver cancer and is frequently identified at a late stage, necessitating systemic therapy. However, resistance to first‐line tyrosine kinase inhibitor therapies, such as sorafenib and lenvatinib, remains a significant clinical challenge.
Longtao Zhao   +6 more
wiley   +1 more source

Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice [PDF]

open access: yes, 2017
Allagnat   +71 more
core   +2 more sources

The electrophilic metabolite of kynurenine, kynurenine-CKA, requires C151 in Keap1 to derepress Nrf2. [PDF]

open access: yesRedox Biol
Feng J   +16 more
europepmc   +1 more source

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