Results 231 to 240 of about 56,140 (348)

THE PROTECTIVE ROLE OF NRF2/KEAP1 IN NEUROLOGICAL DISEASE AND OXIDATIVE STRESS-INDUCED CELL DAMAGE

, 2013
Petra Bergström
openalex   +1 more source

Anti‐Neuroinflammation Activity of Essential Oils and Fatty Acids

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Neuroinflammation plays a pivotal role in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease (AD) and Parkinson's disease (PD). Current pharmacological interventions, such as NSAIDs and corticosteroids, are limited by systemic toxicity and insufficient efficacy in targeting chronic neuroinflammatory processes.
Zelong Jin, Yige Song, Ahmed Attia Ahmed Abdelmoaty, Feng Lin, Jiujun Li, Xianyang Chen   +5 more
wiley   +1 more source

Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer. [PDF]

Cancer Res
Gebru MT, Hoffman TE, Boudreau A, Vu N, Han F, Wang P, Folk E, Wu X, Newton J, Foster-Duke KD, Gajda J, Villa S, Yang N, Sandoval CM, Grant C, Wildeboer SE, Buck WR, Hickson JA, Firestone AJ, Kort M, Bennett BD, Shotwell JB, Wilson NS, Stokoe D.   +23 more
europepmc   +1 more source

Dual‐Pathway Defense: Ultramicro‐Pulverised Powder of Polygonum chinense L. and Atractylodes rhizome (PAUP) Rescues Broilers From E. coli‐Triggered Liver Injury Through Modulation of Oxidative Stress and Inflammation

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Reduced Antibiotic residues and resistance concerns: Offers a potential natural alternative to antibiotics for combating E. coli infections in poultry. Provided safer poultry food products: By enhancing liver function, restoring weight gain, and improving feed efficiency, PAUP supports the production of healthier chickens, ultimately contributing to ...
Jia‐Ci Cai, Yan‐Na Guo, Shao‐Shan Liang, Yan Liu, Fu‐Qiang Huang, Qi‐Peng Lv, Lan‐Yi Zhang, Yi Qin, Xiao‐Jing Chen, Yu‐Xin Liang, Yong‐Ming He, Lu‐Ping Tang   +11 more
wiley   +1 more source

Iloprost, a Prostacyclin Analogue, Alleviates Oxidative Stress and Improves Development of Parthenogenetic Porcine Embryos via Nrf2/Keap1 Signaling. [PDF]

Antioxidants (Basel)
Choi EY, Uh K, Lee SB, Jeong PS, Kang HG, Jeon SB, Yun JH, Son HC, Lim KS, An YJ, Kim SU, Cho SK, Song BS.   +12 more
europepmc   +1 more source

Hepatoprotective Effect of Morchella Mycelia Polysaccharides on Alcoholic Liver Injury and Its Mechanism Involving the Modulation of NOD‐Like Receptor Signaling Pathway

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The Morchella mycelium polysaccharide (MP), a homogeneous α‐glucan (96.555% glucose, 5.7 kDa), protects against alcohol‐induced liver injury in mice. It reduces serum ALT/AST, improves lipid metabolism, and enhances antioxidants and inhibiting lipid peroxidation. Mechanistically, the MP suppresses Nlrp3 inflammasome‐mediated inflammation/pyroptosis and
Xinyu Hu, Qinghu Duan, Leran Ma, Tianyuan Zhang, Mengdan Zhai, Zewei Chen, Wangqi Li, Kaiwen Huang, Yan Ma, Yuchen Zhang, Zhen Wang   +10 more
wiley   +1 more source

Curcumin induces ferroptosis in hepatocellular carcinoma by regulating the P62-KEAP1-NRF2-signaling pathway. [PDF]

BMC Cancer
Deng J, Wu Z, Ning S, Chang X, Liu J, Yu Y, Zhang M, Zhang L.   +7 more
europepmc   +1 more source

NRF2 pathway activation by KEAP1 inhibition attenuates the manifestation of aging phenotypes in salivary glands

, 2020
Sisca Meida Wati, Daisuke Matsumaru, Hozumi Motohashi   +2 more
openalex   +1 more source

Post‐Covid Alzheimer and Its Remediation via PROTACs Therapy: A Comprehensive Review

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Alzheimer's disease (AD) is a progressive neurodegenerative disorder of aging characterized by memory loss and cognitive decline, associated with amyloid‐β toxicity, tau hyperphosphorylation, and neurofibrillary tangle formation. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) affects the central nervous system
Teesta Bhowmick, Ritojo Basu, Arup Kumar Mitra, Sk Asfaque Ali, Ajoy Kumer, Bikram Dhara   +5 more
wiley   +1 more source

CircMAN1A2 Levels Determine GBM Susceptibility to TMZ in a Pathway Involving TEP1‐ and KEAP1‐Mediated NRF2 Degradation Leading to Ferroptosis [PDF]

Xinqiao Li, Jinpeng Hu, Wei Zheng, Zhigang Fan, Hao Chi, Hao Li, Yongfeng Wang, Zhitao Jing   +7 more
openalex   +1 more source