Results 241 to 250 of about 56,140 (348)

Paeoniflorin Ameliorates Spinal Cord Injury by Controlling Apoptosis and Ferroptosis in H2O2‐Damaged PC12 Cells

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
ABSTRACT Background Spinal cord injury (SCI) leads to severe neurological dysfunction. Current therapeutic strategies remain limited, with poor recovery rates. Oxidative stress and ferroptosis are key mechanisms underlying secondary SCI. Paeoniflorin has anti‐inflammatory, antioxidant, and neuroprotective properties; however, its role in regulating ...
Zongyu Zhang, Zhijing Zhou, Peng Zhang, Yongfeng Huo   +3 more
wiley   +1 more source

Tumor suppressor genes and KRAS G12C inhibitor resistance in non-small cell lung cancer. [PDF]

iScience
Zhu L, Jia X, Xu L, Chen L, Fu X, Yan H, Ai B, Peng S.   +7 more
europepmc   +1 more source

5-(3-(N-(Carboxymethyl)naphthalene-2-sulfonamido)phenyl)-1-ethyl-1H-pyrrole-2-carboxylic acid as a Keap1–Nrf2 inhibitor for cerebral ischemia/reperfusion injury treatment

Nanjia Cairang, Yanran Wu, Shumeng Zhi, Jiaqin Tang, Xin Tie, Dong‐Yun Zhan, Guangyuan Lu, Ying Shi, Qipeng Zhao   +8 more
openalex   +2 more sources

<p>Honey and Chamomile Activate Keratinocyte Antioxidative Responses via the KEAP1/NRF2 System</p>

, 2020
Tatsuya Ogawa, Yosuke Ishitsuka, Yoshiyuki Nakamura, Naoko Okiyama, Rei Watanabe, Yasuhiro Fujisawa, Manabu Fujimoto   +6 more
openalex   +2 more sources

Elucidation of Sulforaphane‐Mediated Effects on the Cellular Human Metabolome Using Metabolic Profiling

Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Sulforaphane (SFN) is an isothiocyanate derived from broccoli and is related to various health‐promoting effects. By using metabolic profiling on the hepatoblastoma cell line HepG2 several effects on pathways such as TCA cycle, urea cycle and redox metabolism through SFN were identified.
Nadine Bieß, Hans‐Ulrich Humpf, Matthias Behrens, Andrea Gerdemann   +3 more
wiley   +1 more source

Nrf2-Keap1 Pathway and NLRP3 Inflammasome in Parkinson's Disease: Mechanistic Crosstalk and Therapeutic Implications. [PDF]

Mol Neurobiol
Jain R, Vora L, Nathiya D, Khatri DK.
europepmc   +1 more source

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction [PDF]

Joshua M. Mesfin, Kendal P. Carrow, Alexander Chen, Madeline P. Hopps, Jürgen Holm, Quincy P. Lyons, Michael Nguyen, Jervaughn D. Hunter, Assa Magassa, Elizabeth Wong, Kate E. Reimold, Sriya N. Paleti, Emily Gardner, Matthew P. Thompson, Colin Luo, Xiaoyu Zhang, Karen L. Christman, Nathan C. Gianneschi   +17 more
openalex   +1 more source

Moringa oleifera Lam. As a Herbal Antioxidant‐Enriched Semen Extender in Cryopreservation: A Critical Review of Its Protective Potential

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Moringa oleifera extract protects cryopreserved sperm by scavenging reactive oxygen species and reducing oxidative stress. It enhances antioxidant enzyme activity, including superoxide dismutase, catalase and glutathione peroxidase, thereby maintaining cellular redox balance.
Amir Masoud Firouzabadi, Hadi Zare‐Zardini, Farzaneh Fesahat   +2 more
wiley   +1 more source

Apelin-13 Attenuates Blood-Brain Barrier Dysfunction Following Intracerebral Hemorrhage via Targeting the Keap1/Nrf2 Signaling. [PDF]

CNS Neurosci Ther
Guo P, Siddique R, Qian J, Qi L, Yong VW, Xue M.   +5 more
europepmc   +1 more source

Neuroprotective effect of acetoxypachydiol against oxidative stress through activation of the Keap1-Nrf2/HO-1 pathway [PDF]

Yu Qi, Ge Liu, Shengjie Jin, Jian Rong, Ziqiang Zou, Chenjing Wang, Yuanlong Zhang, Min Zhao, Haoru Zhu, Pengcheng Yan   +9 more
openalex   +1 more source