Results 191 to 200 of about 6,637 (212)
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Expression of highly sulfated keratan sulfate synthesized in human glioblastoma cells

Biochemical and Biophysical Research Communications, 2008
Keratan sulfate (KS) proteoglycan is expressed in the extracellular matrix or cell surface in numerous tissues, predominantly in those of the cornea, cartilage, and brain. However, its structure, function, and regulation remain poorly understood. Our investigation of KS expression in glioblastoma cell lines using Western-blot and flow cytometry with ...
Norihito, Hayatsu   +4 more
openaire   +2 more sources

Immunohistochemical localization of keratan sulfate in the chinchilla inner ear

Hearing Research, 1997
Keratan sulfate (KS) was immunolocalized in the chinchilla cochlea and vestibular system using indirect immunohistochemistry and a monoclonal antibody (clone 5-D-4) directed against a proteoglycan core antigen. As a positive control, anti-KS Mab reactivity was found in the pericellular matrix and lacuna walls of temporal bone osteocytes. In the cochlea,
D J, Swartz, P A, Santi
openaire   +2 more sources

Structure and biological functions of keratan sulfate proteoglycans

1994
The skeletal and corneal keratan sulfate proteoglycans show a different metabolic and structural heterogeneity. The domain structure of the carbohydrate chain has been shown to be different in various animal species. There are two major types of skeletal keratan sulfate proteoglycans with and without fucose.
openaire   +2 more sources

Keratan Sulfate Gal-6-Sulfotransferase

2002
Keratan sulfate (KS) is composed of the repeating disaccharide unit of Galβ1-4GlcNAc (poly-N-acetyllactosamine) with sulfate groups at the 6-position of the Gal and GlcNAc residues. Most GlcNAc residues and half of the Gal residues of corneal KS are sulfated, suggesting that sulfation of the Gal residue occurs after sulfation of the GlcNAc residue and ...
Masakazu Fukuta, Osami Habuchi
openaire   +1 more source

Functional Consequences of Keratan Sulfate Sulfation in Electrosensory Tissues and in Neuronal Regulation

Advanced Biosystems, 2019
AbstractKeratan sulfate (KS) is a functional electrosensory and neuro‐instructive molecule. Recent studies have identified novel low sulfation KS in auditory and sensory tissues such as the tectorial membrane of the organ of Corti and the Ampullae of Lorenzini in elasmobranch fish.
openaire   +2 more sources

A Low Sulfated Keratan Sulfate-like Substance in Rabbit Femur

The Journal of Biochemistry, 1974
M, Masubuchi, Z, Yosizawa
openaire   +2 more sources

Keratan sulfate: structure, biosynthesis, and function.

Glycobiology, 2000
The last 5 years have seen a marked increase in research on keratan sulfate (KS) and a concomitant increase in our understanding of the range of molecules that carry this adaptable polysaccharide. More than 15 KS-linked proteins have been identified and many of the genes encoding these have been cloned.
openaire   +1 more source

Macular corneal dystrophy Lack of keratan sulfate in serum and cornea

Ophthalmic Paediatrics and Genetics, 1986
Gordon K Klintworth   +2 more
exaly  

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