Results 61 to 70 of about 10,728 (217)

Immunohistochemical Detection of Various Proteoglycans in the Extracellular Matrix of Zebra Mussels [PDF]

, 2022
Mussels have been used as animal models for studying ecotoxicology, biomineralization, and bio-adhesion for many years. Despite a wealth of studies on their shell matrix and byssus proteins, few studies have focused on the extracellular matrix molecules ...
Beggel, Sebastian, Geist, Juergen, Milz, Stefan, Schmitz, Christoph, Sternecker, Katharina, Wu, Wenkai   +5 more
core   +1 more source

Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model

Macromolecular Bioscience, EarlyView.
This study reports on 3D‐printed methacrylated gelatin (GelMA) implants designed to serve as corneal stroma substitutes. The implants are characterized for their transparency, mechanical strength, and cytocompatibility. In vivo tests on rabbits demonstrate successful integration, with histopathological analysis showing tissue regeneration, appropriate ...
Deniz Basoz, Aslihan Akalinli, Senem Buyuksungur, A. R. Cenk Celebi, Deniz Yucel, Nesrin Hasirci, Vasif Hasirci   +6 more
wiley   +1 more source

Dimethylmethylene Blue Assay (DMMB)

Bio-Protocol, 2014
Glycosaminoglycans (GAGs) are long unbranched polysaccharides consisting of repeating disaccharide units composed of a hexosamine (glucosamine or galactosamine) and a hexuronic acid (glucuronic or iduronic acid).
Vivien Coulson-Thomas, Tarsis Ferreira
doaj   +1 more source

Distribution and Function of Glycosaminoglycans and Proteoglycans in the Development, Homeostasis and Pathology of the Ocular Surface

Frontiers in Cell and Developmental Biology, 2020
The ocular surface, which forms the interface between the eye and the external environment, includes the cornea, corneoscleral limbus, the conjunctiva and the accessory glands that produce the tear film.
Sudan Puri, Yvette M. Coulson-Thomas, Tarsis F. Gesteira, Tarsis F. Gesteira, Vivien J. Coulson-Thomas   +4 more
doaj   +1 more source

Underpotential deposition of Cu on Au(111) in sulfate-containing electrolytes: a theoretical and experimental study [PDF]

J. Chem. Phys. 104 (1996) 5699, 1995
We study the underpotential deposition of Cu on single-crystal Au(111) electrodes in sulfate-containing electrolytes by a combination of computational statistical-mechanics based lattice-gas modeling and experiments. The experimental methods are in situ cyclic voltammetry and coulometry and ex situ Auger electron spectroscopy and low-energy electron ...
arxiv   +1 more source

Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats

VIEW, EarlyView.
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou, Qiancheng Mao, Junpeng Chi, Jiankun Zhang, Hao Guo, Jitao Wu, Yuanshan Cui   +6 more
wiley   +1 more source

Three-dimensional culture of human meniscal cells: Extracellular matrix and proteoglycan production

BMC Biotechnology, 2008
Background The meniscus is a complex tissue whose cell biology has only recently begun to be explored. Published models rely upon initial culture in the presence of added growth factors. The aim of this study was to test a three-dimensional (3D) collagen
Norton H James, Ingram Jane A, Chow Yin, Mauerhan David, Gruber Helen E, Hanley Edward N, Sun Yubo   +6 more
doaj   +1 more source

Genotype–Phenotype Correlations in Corneal Dystrophies: Advances in Molecular Genetics and Therapeutic Insights

Clinical &Experimental Ophthalmology, Volume 53, Issue 3, Page 232-245, April 2025.
ABSTRACT Corneal dystrophies are a group of predominantly rare inherited disorders. They are by definition bilateral, relatively symmetrical, and without systemic involvement, affecting corneal transparency and/or refraction. Traditional classification of corneal dystrophies is based on slit‐lamp appearance, affected corneal layer and histological ...
Petra Liskova, Pavlina Skalicka, Lubica Dudakova, Andrea L. Vincent   +3 more
wiley   +1 more source

A molecular and histological characterization of cartilage from patients with Morquio syndrome [PDF]

, 2007
SummaryObjectiveTo investigate the gene expression profile and the histological aspects of articular cartilage of patients affected by Morquio syndrome, a lysosomal storage disease characterized by the accumulation of glycosaminoglycans within the cells ...
A. Facchini, B. Grigolo, Blanco, Braisford, Di Ferrante, Fukuda, G. Desando, Grigolo, Grigolo, Horwitz, Iwata, Kalteis, L. De Franceschi, L. Roseti, Lind, Luyten, Maroudas, Martin, Matalon, Mayne, Mikles, Morquio, Nelson, Rezvi, Singh, Tomatsu, Tomatsu, Tomatsu, Trojak, van der Horst   +29 more
core   +1 more source

Role of Biomarkers in Diagnosing Disease, Assessing the Severity and Progression of Disease, and Evaluating the Efficacy of Therapies

Journal of Inherited Metabolic Disease, Volume 48, Issue 3, May 2025.
ABSTRACT This paper reviews biomarkers in lysosomal disease according to their categories and definitions. There are numerous biomarkers in lysosomal diseases. Some are disease or organ‐specific, but most are not. Organ‐specific biomarkers are especially useful, but most biomarkers help with diagnosis, assessing disease severity, prognosis, and ...
Raphael Schiffmann
wiley   +1 more source