Results 1 to 10 of about 190,649 (306)
Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation [PDF]
Exploration of Immunology, 2021 Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 receptor 2 (IL-10R2).
Masutaka Furue, Mihoko Furue
doaj +2 more sources
Agent based modelling helps in understanding the rules by which fibroblasts support keratinocyte colony formation [PDF]
, 2008 Background: Autologous keratincoytes are routinely expanded using irradiated mouse fibroblasts and bovine serum for clinical use. With growing concerns about the safety of these xenobiotic materials, it is desirable to culture keratinocytes in media ...
A Macieira-Coelho +90 more
core +19 more sources
Cell Death Discovery, 2022 Keratinocyte necroptosis (with proinflammatory characteristic) is required for epidermal damage in contact hypersensitivity (CHS). In DNCB-induced CHS mice model, we observed the aggravated keratinocyte death and increased phosphorylation level of MLKL ...
Ni Lian +12 more
doaj +1 more source
Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. [PDF]
PLoS ONE, 2009 The human epidermis is comprised of several layers of specialized epithelial cells called keratinocytes. Normal homoeostasis of the epidermis requires that the balance between keratinocyte proliferation and terminal differentiation be tightly regulated ...
Frances E Lock, Neil A Hotchin
doaj +1 more source
Purple Corn Silk Extract Attenuates UVB-Induced Inflammation in Human Keratinocyte Cells
Scientia Pharmaceutica, 2022 UVB is a causative factor for severe skin damage, such as cell aging, death, and inflammation. UVB easily permeates into the epidermis layer of human skin, which is mainly composed of keratinocyte cells.
Watcharaporn Poorahong +3 more
doaj +1 more source
Nature Communications, 2023 The role of keratinocyte subpopulations in the different phases of the viral cycle during HPV16 infection remains to be characterised. Here, single cell RNA sequencing of HPV16 infected and uninfected organoids identifies 12 distinct keratinocyte ...
Mary C. Bedard +33 more
doaj +1 more source
Frontiers in Immunology, 2021 Matrix stiffness, a critical physical property of the cellular environment, is implicated in epidermal homeostasis. In particular, matrix stiffening during the pathological progression of skin diseases appears to contribute to cellular responses of ...
Hyewon Chung +8 more
doaj +1 more source
Gain-of-function of TRPM4 predisposes mice to psoriasiform dermatitis
Frontiers in Immunology, 2022 Transient receptor potential melastatin 4 (TRPM4) is a Ca2+-activated, monovalent cation channel that is expressed in a wide range of cells. We previously reported two gain-of-function (GoF) mutations of TRPM4 as the cause of progressive symmetric ...
Daisuke Yamada +8 more
doaj +1 more source
Usefulness of Kaloderm® in Finger Tip Necrosis : A Case Report [PDF]
Kosin Medical Journal, 2021 We experienced a case of crush injury of the hand for which we performed a flap surgery and treated the necrotic parts placement using cultured allogeneic keratinocytes (Kaloderm®) with good results.
Chung-Min Yoon +2 more
doaj +1 more source
Aldefluor protocol to sort keratinocytes stem cells from skin [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To investigate the use Aldefluor® and N, N - Dimethylaminobenzaldehyde (DEAB) to design a protocol to sort keratinocyte stem cells from cultured keratinocytes from burned patients.
Samuel Marcos Ribeiro Noronha +5 more
doaj +1 more source