Results 11 to 20 of about 127,048 (215)

C10orf99/GPR15L Regulates Proinflammatory Response of Keratinocytes and Barrier Formation of the Skin

open access: yesFrontiers in Immunology, 2022
The epidermis, outermost layer of the skin, forms a barrier and is involved in innate and adaptive immunity in an organism. Keratinocytes participate in all these three protective processes.
Teruki Dainichi   +20 more
doaj   +1 more source

Impact of p53 Knockout on Protein Data Set of HaCaT Cells in Confluent and Subconfluent Conditions

open access: yesData, 2022
The immortalized keratinocytes, HaCaT, are a popular model for skin research (toxicity, irritation, allergic reactions, or interaction of cells). They maintain a stable keratinocyte phenotype and respond to keratinocyte differentiation stimuli.
Alexander L. Rusanov   +7 more
doaj   +1 more source

Primary Cilia in the Skin: Functions in Immunity and Therapeutic Potential

open access: yesFrontiers in Cell and Developmental Biology, 2021
The skin is the biggest organ and provides a physical and immunological barrier against pathogen infection. The distribution of primary cilia in the skin of mice has been reported, but which cells in human skin have them has not, and we still know very ...
Manami Toriyama   +5 more
doaj   +1 more source

Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema

open access: yesBMC Pulmonary Medicine, 2005
Background Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte ...
Marchal Joëlle   +8 more
doaj   +1 more source

Psoriatic Dermal-derived Mesenchymal Stem Cells Reduce Keratinocyte Junctions, and Increase Glycolysis

open access: yesActa Dermato-Venereologica, 2020
Although it is known that psoriatic dermal-derived mesenchymal stem cells (DMSCs) dysregulate keratinocyte proliferation, the biological activity profile of keratinocytes influenced by psoriatic DMSCs remain unknown. In the present study, we assessed the
Junqin Li   +13 more
doaj   +1 more source

Keratinocyte-Immune Cell Crosstalk in a STAT1-Mediated Pathway: Novel Insights Into Rosacea Pathogenesis

open access: yesFrontiers in Immunology, 2021
Rosacea is a common chronic inflammatory condition that mainly affects the central face. However, the molecular background of the normal central face and the transcriptional profiling and immune cell composition of rosacea lesions remain largely unknown.
Zhili Deng   +41 more
doaj   +1 more source

A comparison of the direct medical costs for individuals with or without basal or squamous cell skin cancer: A study from Australia

open access: yesSAGE Open Medicine, 2016
Objectives: The composition of the medical costs incurred by people treated for basal cell and squamous cell carcinomas (hereafter keratinocyte cancers) is not adequately understood.
David Rowell   +3 more
doaj   +1 more source

Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes

open access: yesFrontiers in Microbiology, 2020
Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa   +9 more
doaj   +1 more source

Lactobacillus rhamnosus GG Lysate Increases Re-Epithelialization of Keratinocyte Scratch Assays by Promoting Migration

open access: yesScientific Reports, 2015
A limited number of studies have investigated the potential of probiotics to promote wound healing in the digestive tract. The aim of the current investigation was to determine whether probiotic bacteria or their extracts could be beneficial in cutaneous
Walaa Mohammedsaeed   +3 more
doaj   +1 more source

Anti-Atopic Dermatitis Activity of Epi-Oxyzoanthamine Isolated from Zoanthid

open access: yesMarine Drugs, 2023
Atopic dermatitis (AD, eczema) is a condition that causes dry, itchy, and inflamed skin and occurs most frequently in children but also affects adults. However, common clinical treatments provide limited relief and have some side effects.
Chieh-Chen Huang   +8 more
doaj   +1 more source

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