Results 21 to 30 of about 182,642 (309)
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
Journal of Cell Biology, 1988 In contrast to mouse epidermal cells, human skin keratinocytes are rather resistant to transformation in vitro. Immortalization has been achieved by SV40 but has resulted in cell lines with altered differentiation.
P. Boukamp +5 more
semanticscholar +1 more source
Primary Cilia in the Skin: Functions in Immunity and Therapeutic Potential
Frontiers in Cell and Developmental Biology, 2021 The skin is the biggest organ and provides a physical and immunological barrier against pathogen infection. The distribution of primary cilia in the skin of mice has been reported, but which cells in human skin have them has not, and we still know very ...
Manami Toriyama +5 more
doaj +1 more source
Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema
BMC Pulmonary Medicine, 2005 Background Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte ...
Marchal Joëlle +8 more
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Acta Dermato-Venereologica, 2020 Although it is known that psoriatic dermal-derived mesenchymal stem cells (DMSCs) dysregulate keratinocyte proliferation, the biological activity profile of keratinocytes influenced by psoriatic DMSCs remain unknown. In the present study, we assessed the
Junqin Li +13 more
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Frontiers in Immunology, 2021 Rosacea is a common chronic inflammatory condition that mainly affects the central face. However, the molecular background of the normal central face and the transcriptional profiling and immune cell composition of rosacea lesions remain largely unknown.
Zhili Deng +41 more
doaj +1 more source
SAGE Open Medicine, 2016 Objectives: The composition of the medical costs incurred by people treated for basal cell and squamous cell carcinomas (hereafter keratinocyte cancers) is not adequately understood.
David Rowell +3 more
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Antiviral and Immunomodulatory Properties of Antimicrobial Peptides Produced by Human Keratinocytes
Frontiers in Microbiology, 2020 Keratinocytes, the main cells of the epidermis, are the first site of replication as well as the first line of defense against many viruses such as arboviruses, enteroviruses, herpes viruses, human papillomaviruses, or vaccinia virus.
Céline Chessa +9 more
doaj +1 more source
Anti-Atopic Dermatitis Activity of Epi-Oxyzoanthamine Isolated from Zoanthid
Marine Drugs, 2023 Atopic dermatitis (AD, eczema) is a condition that causes dry, itchy, and inflamed skin and occurs most frequently in children but also affects adults. However, common clinical treatments provide limited relief and have some side effects.
Chieh-Chen Huang +8 more
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Interleukin-22 and keratinocytes; pathogenic implications in skin inflammation
Exploration of Immunology, 2021 Interleukin (IL)-22 is produced from immune cells such as T helper (Th)22 cells, Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL-22R1) and the IL-10 receptor 2 (IL-10R2).
Masutaka Furue, Mihoko Furue
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Keratinocyte exosomes activate neutrophils and enhance skin inflammation in psoriasis
The FASEB Journal, 2019 Psoriasis is a chronic inflammatory skin disease that severely affects patients physiologically and psychologically. The pathogenesis involving communication between psoriatic keratinocytes and infiltrated immune cells such as neutrophils remains unclear.
Man Jiang +7 more
semanticscholar +1 more source