Results 1 to 10 of about 322,086 (387)

Agent based modelling helps in understanding the rules by which fibroblasts support keratinocyte colony formation [PDF]

, 2008
Background: Autologous keratincoytes are routinely expanded using irradiated mouse fibroblasts and bovine serum for clinical use. With growing concerns about the safety of these xenobiotic materials, it is desirable to culture keratinocytes in media ...
A Macieira-Coelho, A Szabowski, AJ Bogaerdt, AJ Bullock, BM Kim, BS Croix, C Clavel, CA Harrison, CC Chang, CG Tepper, CM Nelson, CS Osborne, D Drasdo, D Morel, E Kolettas, EAG Blomme, ER Waelti, Eshel Ben-Jacob, F Goulet, F Takeuchi, FA Meineke, FY Bhora, G Hubner, GG Gallico, GTB Casella, H Smola, H Uchi, HJ Stark, HJ Wearing, I Scheffrahn, I Sher, IR Williams, J Ashkenas, J Gailit, J Galle, J Grossmann, J Kopp, J Rashbass, JC Adams, JG Rheinwald, JL Walker, JM Ponciano, JM Sorrell, JS Rubin, JV Gorelik, K Orford, K Suzuki, L Mishra, LY Zhang, M Absher, M Okazaki, M Sakaguchi, M Sibilia, MC Higham, Mike Holcombe, MN Szabowski, MR Owen, MT Santini, N Grabe, N Matsuyoshi, NT Dai, P Angel, Phil McMinn, R Fleischmajer, R Roguet, RA Dawson, RK Assoian, Rod Smallwood, RP Witte, S Coakley, S Kansra, S MacNeil, S Tagashira, S Werner, Sheila MacNeil, SN Bhatia, T Sun, T Sun, T Sun, T Sun, TA Beyer, Tao Sun, TB Gizelda, TK Dilley, U Keller, U Mirastschijski, UB Jensen, W Bowers, W Sabine, Y Kanzaki, Y Yamaguchi   +90 more
core   +21 more sources

Emerging roles of keratinocytes in nociceptive transduction and regulation

Frontiers in Molecular Neuroscience, 2022
Keratinocytes are the predominant block-building cells in the epidermis. Emerging evidence has elucidated the roles of keratinocytes in a wide range of pathophysiological processes including cutaneous nociception, pruritus, and inflammation ...
Xiaohan Xu, Catherine Yu, Catherine Yu, Catherine Yu, Li Xu, Jijun Xu, Jijun Xu, Jijun Xu   +7 more
doaj   +1 more source

Updated Perspectives on Keratinocytes and Psoriasis: Keratinocytes are More Than Innocent Bystanders

Psoriasis, 2022
Psoriasis is a complex disease triggered by genetic, immunologic, and environmental stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes, some of which are critical in keratinocyte biology and epidermal barrier ...
Laura I. Ortiz-López, V. Choudhary, W. Bollag   +2 more
semanticscholar   +1 more source

Keratinocytes Regulate the Threshold of Inflammation by Inhibiting T Cell Effector Functions

Cells, 2021
Whilst the importance of keratinocytes as a first-line defense has been widely investigated, little is known about their interactions with non-resident immune cells.
Peter Seiringer, Stefanie Eyerich, Kilian Eyerich, Daniela Dittlein, Anna Caroline Pilz, Emanuele Scala, Johannes Ring, Heidrun Behrendt, Andrea Cavani, Claudia Traidl-Hoffmann   +9 more
doaj   +1 more source

Unraveling Transcriptome Profile, Epigenetic Dynamics, and Morphological Changes in Psoriasis-like Keratinocytes: “Insights into Similarity with Psoriatic Lesional Epidermis”

Cells, 2023
Keratinocytes are one of the primary cells affected by psoriasis inflammation. Our study aimed to delve deeper into their morphology, transcriptome, and epigenome changes in response to psoriasis-like inflammation.
Ameneh Ghaffarinia, Szilárd Póliska, Ferhan Ayaydin, Aniko Goblos, Shahram Parvaneh, Máté Manczinger, Fanni Balogh, Lilla Erdei, Zoltán Veréb, Kornélia Szabó, Zsuzsanna Bata-Csörgő, Lajos Kemény   +11 more
doaj   +1 more source

Keratinocyte Carcinoma [PDF]

CA: A Cancer Journal for Clinicians, 2003
Keratinocyte carcinoma is by far the most common cancer in the United States. Basal cell carcinomas and squamous cell carcinomas account for approximately 80% and 20% of cases of KC, respectively. The term nonmelanoma skin cancer is commonly used to refer to squamous cell carcinomas and basal cell carcinomas; however, other types of nonmelanoma skin ...
Michael R, Albert, Martin A, Weinstock
openaire   +2 more sources

The Immune Functions of Keratinocytes in Skin Wound Healing

International Journal of Molecular Sciences, 2020
As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair not only as structural cells but also exerting important immune functions.
M. Piipponen, Dongqing Li, N. Landén
semanticscholar   +1 more source

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

Cells, 2020
Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +8 more
doaj   +1 more source

In Vitro Differentiation of Human Skin-Derived Cells into Functional Sensory Neurons-Like

Cells, 2020
Skin-derived precursor cells (SKPs) are neural crest stem cells that persist in certain adult tissues, particularly in the skin. They can generate a large type of cell in vitro, including neurons.
Adeline Bataille, Raphael Leschiera, Killian L’Hérondelle, Jean-Pierre Pennec, Nelig Le Goux, Olivier Mignen, Mehdi Sakka, Emmanuelle Plée-Gautier, Cecilia Brun, Thierry Oddos, Jean-Luc Carré, Laurent Misery, Nicolas Lebonvallet   +12 more
doaj   +1 more source

Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin

JCI Insight, 2020
The skin serves as the primary interface between our body and the external environment and acts as a barrier against entry of physical agents, chemicals, and microbes. Keratinocytes make up the main cellular constitute of the outermost layer of the skin,
Yanyun Jiang, L. Tsoi, A. Billi, Nicole L. Ward, Paul W. Harms, C. Zeng, E. Maverakis, J. Kahlenberg, J. Gudjonsson   +8 more
semanticscholar   +1 more source