Results 21 to 30 of about 322,086 (387)

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization

Protein & Cell, 2017
Cutaneous neurogenic inflammation (CNI) is inflammation that is induced (or enhanced) in the skin by the release of neuropeptides from sensory nerve endings. Clinical manifestations are mainly sensory and vascular disorders such as pruritus and erythema.
Olivier Gouin, Killian L’Herondelle, Nicolas Lebonvallet, Christelle Le Gall-Ianotto, Mehdi Sakka, Virginie Buhé, Emmanuelle Plée-Gautier, Jean-Luc Carré, Luc Lefeuvre, Laurent Misery, Raphaele Le Garrec   +10 more
doaj   +1 more source

Counteracting the Ramifications of UVB Irradiation and Photoaging with Swietenia macrophylla King Seed

Molecules, 2021
In this day and age, the expectation of cosmetic products to effectively slow down skin photoaging is constantly increasing. However, the detrimental effects of UVB on the skin are not easy to tackle as UVB dysregulates a wide range of molecular changes ...
Camille Keisha Mahendra, Syafiq Asnawi Zainal Abidin, Thet Thet Htar, Lay-Hong Chuah, Shafi Ullah Khan, Long Chiau Ming, Siah Ying Tang, Priyia Pusparajah, Bey Hing Goh   +8 more
doaj   +1 more source

Expression and Functional Studies on the Noncoding RNA, PRINS. [PDF]

, 2012
PRINS, a noncoding RNA identified earlier by our research group, contributes to psoriasis susceptibility and cellular stress response. We have now studied the cellular and histological distribution of PRINS by using in situ hybridization and demonstrated
Amin, Anikó Göblös, Attila Dobozy, Bata-Csorgo, Bata-Csorgo, Belso, Beylot-Barry, Borer, Bos, Bos, Bowcock, Bowcock, Carlen, Di Carlo, Duffy, Feuerstein, Feuerstein, Feuerstein, Feuerstein, Hernandez-Verdun, István Németh, Itahana, Krisztina Szegedi, Krueger, Kurki, Lajos Kemény, Lebwohl, Lee, Lindstrom, Livak, Mattick, Moll, Mária Antal, Márta Széll, Nomura, Palaniswamy, Papadopoulou, Peter, Pivarcsi, Pivarcsi, Polyanka, Rinn, Sarolta Bacsa, Sonkoly, Spector, Stoeckman, Szegedi, Szell, Szymanski, Takemura, Tarapore, Tiedge, Ting, Van Hooser, Wang, Wu, Yogev, Yusufzai, Zalfa, Zaric, Zhou, Zsuzsanna Bata-Csörgő   +61 more
core   +2 more sources

Role of Keratinocytes in Sensitive Skin

Frontiers in Medicine, 2019
Sensitive skin is a clinical syndrome defined by the occurrence of unpleasant sensations such as burning, stinging, tingling, pricking, or itching in response to various normally innocuous physical, chemical, and thermal stimuli.
Matthieu Talagas, Matthieu Talagas, Laurent Misery, Laurent Misery   +3 more
doaj   +1 more source

Secreted Factors from Keloid Keratinocytes Modulate Collagen Deposition by Fibroblasts from Normal and Fibrotic Tissue: A Pilot Study

Biomedicines, 2020
Interactions between keratinocytes and fibroblasts in the skin layers are crucial in normal tissue development, wound healing, and scarring. This study has investigated the role of keloid keratinocytes in regulating collagen production by primary ...
Mansour A. Alghamdi, Laith N. AL-Eitan, Andrew Stevenson, Nutan Chaudhari, Nicole Hortin, Hilary J. Wallace, Patricia L. Danielsen, Mitali Manzur, Fiona M. Wood, Mark W. Fear   +9 more
doaj   +1 more source

Centipeda minima Extract Inhibits Inflammation and Cell Proliferation by Regulating JAK/STAT Signaling in Macrophages and Keratinocytes

Molecules, 2023
Psoriasis, a chronic inflammation-mediated skin disease, affects 2–3% of the global population. It is characterized by keratinocyte hyperproliferation and immune cell infiltration.
Yuanqiang Ma, Byoung Ha Kim, Sang Kyu Yun, Yoon-Seok Roh   +3 more
doaj   +1 more source

Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. [PDF]

, 2003
Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection.
Cogen, Anna L, Lau, Helen Y, Monteleon, Christine L, Moore, Thomas A, Standiford, Theodore J   +4 more
core   +1 more source

The histopathological spectrum of acute generalized exanthematous pustulosis (AGEP) and its differentiation from generalized pustular psoriasis [PDF]

, 2010
Background: Acute generalized exanthematous pustulosis (AGEP) represents a severe, acute, pustular skin reaction that is most often induced by drugs. AGEP can be difficult to differentiate from generalized pustular psoriasis (GPP) both clinically and ...
Austin, Baker, Beylot, Beylot, Britschgi, Burrows, Farber, Friedman, Guevara-Gutierrez, Horn, Iizuka, Kardaun, Katz, Keller, Kingery, Macmillan, Mobini, Muller, Naldi, Roujeau, Roujeau, Schaefer, Schmid, Shelley, Shelley, Sidoroff, Sidoroff, Smith, Spencer, Staughton, Terui, Weedon, Weedon, Yawalkar, Zelickson   +34 more
core   +3 more sources

Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities

PAIN Reports, 2016
. Introduction: Epidermal keratinocytes are increasingly recognized as active participants in the sensory transduction of itch and pain, processes known to involve primary afferent glutamatergic neurons.
David Cabañero, Takeshi Irie, Marta Celorrio, Christopher Trousdale, David M. Owens, David Virley, Phillip J. Albrecht, Michael J. Caterina, Frank L. Rice, Jose A. Morón   +9 more
doaj   +1 more source

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]

, 2016
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir, Banning, Antje, Eming, Rüdiger, Exner, Yvonne, Hertl, Michael, Kurrle, Nina, Tikkanen, Ritva, Völlner, Frauke   +7 more
core   +1 more source