Skin grafts : local quest for viable alternatives to autologous grafts using silk and acellular dermal matrices [PDF]
, 2014 The gold standard with regards to skin transplantation is the use of the patient’s own skin obtained from a healthy donor site. Such grafts can be either full thickness skin or more commonly nowadays, split thickness skin.
Gialanzè, Yanika +2 more
core +1 more source
The histopathological spectrum of acute generalized exanthematous pustulosis (AGEP) and its differentiation from generalized pustular psoriasis [PDF]
, 2010 Background: Acute generalized exanthematous pustulosis (AGEP) represents a severe, acute, pustular skin reaction that is most often induced by drugs. AGEP can be difficult to differentiate from generalized pustular psoriasis (GPP) both clinically and ...
Austin +34 more
core +3 more sources
Mammalian Epidermis: A Compendium of Lipid Functionality
Frontiers in Physiology, 2022 Mammalian epidermis is a striking example of the role of lipids in tissue biology. In this stratified epithelium, highly specialized structures are formed that leverage the hydrophobic properties of lipids to form an impermeable barrier and protect the ...
Matteo Vietri Rudan, Fiona M. Watt
doaj +1 more source
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy [PDF]
, 2017 BACKGROUND. Actinic keratosis is a precursor to cutaneous squamous cell carcinoma. Long treatment durations and severe side effects have limited the efficacy of current actinic keratosis treatments.
Ahu Turkoz +18 more
core +2 more sources
Visualisation of tissue kallikrein, kininogen and kinin receptors in human skin following trauma and in dermal diseases [PDF]
, 2004 During dermal injury and inflammation the serine proteases kallikreins cleave endogenous, multifunctional substrates (kininogens) to form bradykinin and kallidin.
Bhoola, Kanti D. +7 more
core +1 more source
Differentiation-dependent glycosylation of cells in squamous cell epithelia detected by a mammalian lectin [PDF]
, 2002 The squamous stratified epithelia contain a proliferative (harboring mitotic activity) and a differentiating compartment. Due to the potential of protein-carbohyd rate interactions to regulate cellular activities we introduced a mammalian lectin to cyto-
Dvorankova, Barbora +7 more
core +1 more source
Heat shock protein 90 inhibitor RGRN-305 potently attenuates skin inflammation
Frontiers in Immunology, 2023 IntroductionChronic inflammatory skin diseases may have a profound negative impact on the quality of life. Current treatment options may be inadequate, offering an unsatisfactory response or side effects.
Hakim Ben Abdallah +6 more
doaj +1 more source
Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? [PDF]
, 2016 The role of Notch pathway in tumorigenesis is highly variable. It can be tumor suppressive or pro-oncogenic, typically depending on the cellular context.
Biswas, Sangita +5 more
core +1 more source
EpCAM Induction Functionally Links to the Wnt-Enhanced Cell Proliferation in Human Keratinocytes
Cell Transplantation, 2014 Accelerating proliferation of primary keratinocytes benefits skin autografts for severely burned patients. Wnt signal, a conserved pathway controlling cell cycle and morphogenesis in embryo, also involves in cell proliferation and tumorigenesis in adult ...
Ching-I Shen +7 more
doaj +1 more source
Korean red ginseng extracts alleviate skin damage in heat-stimulated skin cells by suppressing NF-κB activation [PDF]
Archives of Biological SciencesThis study explored the impact of heat stimulation on skin barrier damage, aging, and inflammatory responses by analyzing gene and protein-level changes.
Kim Jeeyoung +4 more
doaj +1 more source