Results 71 to 80 of about 98,344 (203)
Recent advances in plant kinetochore research
Frontiers in Cell and Developmental BiologyFaithful chromosome segregation is crucial for cell division in eukaryotes, facilitated by the kinetochore, a multi-subunit protein complex that connects chromosomes to the spindle microtubules.
Elena Kozgunova, Elena Kozgunova
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Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores
Cells, 2019 Faithful chromosome segregation during mitosis is crucial for maintaining genome stability. The spindle assembly checkpoint (SAC) is a surveillance mechanism that ensures accurate mitotic progression.
Zhen Dou +5 more
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Establishment of the vertebrate kinetochores [PDF]
Chromosome Research, 2012 The centromere is essential for accurate chromosome segregation during mitosis and meiosis to achieve transmission of genetic information to daughter cells. To facilitate accurate chromosome segregation, the centromere serves several specific functions, including microtubule binding, spindle-checkpoint control, and sister chromatid cohesion.
Tetsuya, Hori, Tatsuo, Fukagawa
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Plant kinetochore complex: composition, function, and regulation
Frontiers in Plant ScienceThe kinetochore complex, an important protein assembly situated on the centromere, plays a pivotal role in chromosome segregation during cell division.
Yuqian Xie +5 more
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Kinetochore-associated Stu2 promotes chromosome biorientation in vivo
, 2019 Accurate segregation of chromosomes to daughter cells is a critical aspect of cell division. It requires the kinetochores on duplicated chromosomes to biorient, attaching to microtubules from opposite poles of the cell.
Rena K. Evans (7465595) +8 more
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The roles of kinetochore of micronucleus in mitosis of HeLa cells: a live cell imaging study
Cancer Cell International, 2019 Background Micronuclei (MNi) are extensively used to evaluate genotoxic effects and chromosome instability. However, the roles of kinetochore of MN in mitosis have not been completely addressed.
Erkang Jiang +7 more
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, 2019 A) Exponentially growing stu2-AID cdc20-AID cultures with an ectopically expressed STU2 allele (STU2WT, SBY17369; stu2ccΔ, SBY17371) or without an ectopic allele (no covering allele, SBY17367) that also contained MTW1-3GFP (kinetochore) and SPC42-CFP ...
Rena K. Evans (7465595) +8 more
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Biophysics of Kinetochore Microtubules in Human Mitotic Spindles
, 2022 During eukaryotic cell division, chromosomes are linked to microtubules in the spindle by a macromolecular complex called the kinetochore. Regulation of these bound kinetochore micro- tubules is crucial to ensuring accurate chromosome segregation ...
Conway, William
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Nature Communications, 2016 Ska1 is a kinetochore-localised protein that couples kinetochore movement to microtubule (MT) depolymerisation. Here Thomas et al. show that the MT +TIP binding protein EB1 recruits Ska1 to the MT-kinetochore interface and stabilises the interaction ...
Geethu E. Thomas +12 more
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Ordered Kinetochore Assembly in the Human-Pathogenic Basidiomycetous Yeast
mBio, 2013 Kinetochores facilitate interaction between chromosomes and the spindle apparatus. The formation of a metazoan trilayered kinetochore is an ordered event in which inner, middle, and outer layers assemble during disassembly of the nuclear envelope during ...
Lukasz Kozubowski +8 more
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