Results 21 to 30 of about 16,601 (180)
Frontiers in Neurology, 2019 Purpose: Epilepsy is a highly disabling neurological disorder. Brain insult is the most critical cause of epilepsy in adults. This study aimed to find reliable and efficient biomarkers for predicting secondary epilepsy.Materials and methods: The LiCl ...
Jing Zou +6 more
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Mass-spectrometric identification of T-kininogen I/thiostatin as an acute-phase inflammatory protein suppressed by curcumin and capsaicin. [PDF]
PLoS ONE, 2014 Curcumin and capsaicin are dietary xenobiotics with well-documented anti-inflammatory properties. Previously, the beneficial effect of these spice principles in lowering chronic inflammation was demonstrated using a rat experimental model for arthritis ...
Bina Joe +4 more
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Lisinopril-Induced Angioedema in a Patient with Plasma Prekallikrein Deficiency
TH Open, 2020 Angiotensin-converting enzyme (ACE) inhibitors are extensively prescribed to treat patients with hypertension, congestive heart failure, and diabetic nephropathy.
Swapan K. Dasgupta +2 more
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Isolation and characterization of ornitho‐kininogen [PDF]
European Journal of Biochemistry, 1987 Ornitho‐kininogen was purified from chicken blood plasma by a two‐stage method using chromatography on columns of S‐alkylated papain‐Cellulofine and DEAE‐5PW. The yield was 1.7 mg from 44 ml plasma. The isolated preparation gave a single band on sodium dodecyl sulfate/polyacrylamide gel electrophoresis (SDS‐PAGE) with or without 2‐mercaptoethanol and ...
M, Kimura +5 more
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Towards understanding the kallikrein-kinin system: insights from measurement of kinin peptides
Brazilian Journal of Medical and Biological Research, 2000 The kallikrein-kinin system is complex, with several bioactive peptides that are formed in many different compartments. Kinin peptides are implicated in many physiological and pathological processes including the regulation of blood pressure and sodium ...
D.J. Campbell
doaj +1 more source
Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells.
PLoS Pathogens, 2022 During hematogenously disseminated candidiasis, blood borne fungi must invade the endothelial cells that line the blood vessels to infect the deep tissues.
Quynh T Phan +9 more
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Maternal serum proteomic profiles of pregnant women with type 1 diabetes
Scientific Reports, 2022 Despite improvement in the care of diabetes over the years, pregnancy complicated by type 1 diabetes (T1DM) is still associated with adverse maternal and neonatal outcomes.
Paweł Gutaj +9 more
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Drugs of the Kallikrein–Kinin System: An Overview
Drugs and Drug Candidates, 2023 The kallikrein–kinin system consists of the two kininogen substrates present in the blood plasma, and two serine proteases: the plasma and tissue kallikreins.
François Marceau
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Kininogens Are Antithrombotic Proteins In Vivo [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 1999 Abstract —Kininogens have recently been shown to possess antiadhesive, anticoagulant, and profibrinolytic properties and can inhibit platelet activation at low thrombin concentrations. To test whether kininogens have antithrombotic properties in vivo, we devised a model of limited arterial injury confined to removal of the ...
R W, Colman +4 more
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Kininogen Cleavage Assay: Diagnostic Assistance for Kinin-Mediated Angioedema Conditions. [PDF]
PLoS ONE, 2016 Angioedema without wheals (AE) is a symptom characterised by localised episodes of oedema presumably caused by kinin release from kininogen cleavage. It can result from a hereditary deficiency in C1 Inhibitor (C1Inh), but it can present with normal level
Rémi Baroso +7 more
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