Results 11 to 20 of about 1,354,109 (194)

Gallium-68-Labeled KISS1-54 Peptide for Mapping KISS1 Receptor via PET: Initial Evaluation in Human Tumor Cell Lines and in Tumor-Bearing Mice. [PDF]

Pharmaceuticals (Basel), 2023
Kisspeptins (KPs, KISS1) and their receptor (KISS1R) play a pivotal role as metastasis suppressor for many cancers. Low or lost KP expression is associated with higher tumor grade, increased metastatic potential, and poor prognosis.
Israel I, Riehl G, Butt E, Buck AK, Samnick S.   +4 more
europepmc   +5 more sources

Expression of Kisspeptin (KISS1) and its Receptor GPR54 (KISS1R) in Prostate Cancer [PDF]

Anticancer Research, 2020
Prostate cancer (PCa) is the second most commonly diagnosed cancer in men. In contrast to localized disease, metastatic PCa leads to increased mortality. Kisspeptin (KISS1) functions as a metastasis suppressor in various cancers. The aim of this study was to detect the expression of KISS1 and its receptor GPR54 (KISS1R) in prostate cancer.The ...
Xoxakos, I., Petraki, C., Msauel, P., Armakolas, A., Grigorakis, A., Stefanakis, S., Koutsilieris, M.   +6 more
core   +5 more sources

Biological Significance of Kisspeptin–Kiss 1 Receptor Signaling in the Habenula of Teleost Species [PDF]

Frontiers in Endocrinology, 2018
Kisspeptin is a neuropeptide, encoded by kisspeptin 1 (KISS1)/Kiss1 gene, which primarily acts as the regulator of reproductive functions via its receptor, kisspeptin receptor (KissR) in vertebrates.
Satoshi Ogawa, Ishwar S. Parhar
doaj   +2 more sources

Serum kisspeptin levels mainly depend on ovarian expression of Kiss1 mRNA in female rats [PDF]

Frontiers in Physiology, 2022
The hypothalamic kisspeptin/KISS1 receptor system is essential for puberty onset and reproductive development. Although serum kisspeptin might be associated with puberty, its levels, according to developmental stage, and its origin still remain unclear ...
Ahreum Kwon, Ji Young Eom, Woo Jung Lee, Han Saem Choi, Kyungchul Song, Junghwan Suh, Hyun Wook Chae, Ho-Seong Kim   +7 more
doaj   +2 more sources

Involvement of nuclear receptor corepressor 2 (NCOR2) in estrogen-induced repression of arcuate Kiss1 expression in female rats

The Journal of Reproduction and Development
Hypothalamic arcuate (ARC) kisspeptin neurons are considered the gonadotropin-releasing hormone pulse generator in rats. In virgin rats, the expression of the ARC kisspeptin gene (Kiss1) is repressed by proestrous levels of estradiol-17β (high E2) but ...
Marina TAKIZAWA, Sae MIYAZAKI, Hitomi TSUCHIDA, Mayuko NAGAE, Shunsuke SEKI, Masumi HIRABAYASHI, Fumitaka OSAKADA, Naoko INOUE, Hiroko TSUKAMURA, Yoshihisa UENOYAMA   +9 more
doaj   +2 more sources

Supplemental Material, supplemental_table_1_primer_sequences - Increased Expression of KISS1 and KISS1 Receptor in Human Granulosa Lutein Cells—Potential Pathogenesis of Polycystic Ovary Syndrome

, 2018
Supplemental Material, supplemental_table_1_primer_sequences for Increased Expression of KISS1 and KISS1 Receptor in Human Granulosa Lutein Cells—Potential Pathogenesis of Polycystic Ovary Syndrome by Kai-Lun Hu, Hongcui Zhao, Zheying Min, Yilei He, Tianjie Li, Xiumei Zhen, Yun Ren, Hsun-Ming Chang, Yang Yu, and Rong Li in Reproductive ...
Hu, Kai-Lun, Zhao, Hongcui, Min, Zheying, He, Yilei, Li, Tianjie, Zhen, Xiumei, Ren, Yun, Chang, Hsun-Ming, Yu, Yang, Li, Rong   +9 more
core   +4 more sources

KISS1/KISS1R in Cancer: Friend or Foe?

Frontiers in Endocrinology, 2018
The KISS1 gene encodes KISS1, a protein that is rapidly processed in serum into smaller but biologically active peptides called kisspeptins (KPs). KISS1 and the KPs signal via the G-protein coupled receptor KISS1R.
Stephania Guzman, Stephania Guzman, Muriel Brackstone, Sally Radovick, Sally Radovick, Andy V. Babwah, Andy V. Babwah, Moshmi M. Bhattacharya, Moshmi M. Bhattacharya, Moshmi M. Bhattacharya   +9 more
doaj   +2 more sources

Role of the kisspeptin/KISS1 receptor system in the testicular development of mice. [PDF]

J Chin Med Assoc, 2021
Background: Kisspeptin and its receptor KISS1R have been found to be essential regulators of reproductive function. Previous data have revealed the presence of Kiss1 and Kiss1r mRNAs in the hypothalamus
Chiang CM, Chiu HY, Jong DS, Wu LS, Lee YJ, Chiu CH.   +5 more
europepmc   +7 more sources

Kiss1 and Kiss1 receptor expression in the rhesus monkey testis: a possible local regulator of testicular function

Open Life Sciences, 2013
Abstract
Tariq Amna, Shahab Muhammad, Clarke Iain, Pereira Alda, Smith Jeremy, Khan Saeed-ul-Hasan, Sultan Javeria, Javed Sehrish, Anwar Tayyaba   +8 more
doaj   +2 more sources

KISS1 and KISS1R expression in the human and rat carotid body and superior cervical ganglion [PDF]

European Journal of Histochemistry, 2011
KISS1 and its receptor, KISS1R, have both been found to be expressed in central nervous system, but few data are present in the literature about their distribution in peripheral nervous structures.
A. Porzionato, G. Fenu, M. Rucinski, V. Macchi, A. Montella, L. K. Malendowicz, R. De Caro   +6 more
doaj   +2 more sources