Results 51 to 60 of about 402 (139)

Developing kndy neurons display marked sex differences in Kiss1, Tac2, Tacr3 and sex steroid receptors mRNA levels in utero

, 2017
Developing kndy neurons display marked sex differences in [i]Kiss1[/i], [i]Tac2[/i], [i]Tacr3[/i] and sex steroid receptors mRNA levels [i]in utero[/i]. 3.
Poissenot, Kévin, Alfaia, Caroline, Colledge, William, Faure, Mélanie, Robert, Vincent, Yeo, Shel, Franceschini, Isabelle   +6 more
core   +2 more sources

In vitro differentiation of the hypothalamic KNDy neuron, a master regulator for reproduction, from mouse embryonic stem cells

Reproductive Biology and Endocrinology
Background Hypothalamic kisspeptin neurons are master regulators of reproduction in mammals, including humans and rodents, via direct stimulation of gonadotropin-releasing hormone (GnRH) neurons.
Natsuki Miyake, Hidetaka Suga, Satoko Osuka, Tomomi Seki, Reina Sonehara, Ayako Muraoka, Tomoko Nakamura, Bayasula, Tsutomu Miwata, Mika Soen, Mayu Sakakibara, Shiori Go, Saki Hasegawa, Naoko Inoue, Yoshihisa Uenoyama, Hiroko Tsukamura, Hiroshi Arima, Hiroaki Kajiyama   +17 more
doaj   +1 more source

Menopausal Stage–Specific Associations of Body Fat Content and Total Body Water With Vasomotor Symptoms

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Associations of adiposity and total body water with vasomotor symptoms varied according to menopausal stage. Divergent relationships observed across body composition measures suggest that distinct physiological mechanisms may underlie vasomotor symptoms during the menopausal transition and postmenopause.
Katarzyna Górecka, Monika Krzyżanowska
wiley   +1 more source

Same Fat, Different Consequences? The Association Between Fat Distribution and Vasomotor Menopausal Symptoms Varies by Menopausal Status

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Body fat distribution was associated with vasomotor symptoms in a menopausal stage‐specific manner. Greater trunk and abdominal adiposity were linked to more frequent and bothersome symptoms during perimenopause, whereas distinct abdominal adiposity measures showed contrasting associations with symptom burden after menopause.
Katarzyna Górecka, Monika Krzyżanowska
wiley   +1 more source

New Insights into the Control of Pulsatile GnRH Release: the Role of Kiss1/Neurokinin B Neurons

Frontiers in Endocrinology, 2012
Gonadotropin-releasing hormone (GnRH) is the ultimate output signal of an intricate network of neuroendocrine factors that, acting on the pituitary, trigger gonadotropin release.
Víctor M. Navarro
doaj   +1 more source

Hormone therapy (HT) in women with premature ovarian insufficiency or early menopause: Time to think of a new paradigm for healthy aging. A joint FIGO and IMS position paper

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 26-47, October 2026.
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto, Suvarna S. Khadilkar, Rossella E. Nappi, Andrea R. Genazzani, Federica Frezet, Laura Cucinella, Hema Divakar, Panagiotis Anagnostis, Nick Panay   +8 more
wiley   +1 more source

Divergent effects of hyperandrogenemia on the female reproductive neuroendocrine axis under different physiological conditions

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract The hypothalamic–pituitary–gonadal (HPG) axis coordinates reproductive function and incorporates gonadal sex steroid feedback to regulate gonadotropin secretion in a homeostatic manner. In females, ovarian estrogens and progestins act as the primary negative feedback signals to suppress luteinizing hormone (LH) release, whereas in males ...
Lillian Rose, Alexander S. Kauffman
wiley   +1 more source

Dynamic Hormone Control of Stress and Fertility

Frontiers in Physiology, 2020
Neuroendocrine axes display a remarkable diversity of dynamic signaling processes relaying information between the brain, endocrine glands, and peripheral target tissues.
Eder Zavala, Eder Zavala, Margaritis Voliotis, Tanja Zerenner, Joël Tabak, Jamie J. Walker, Jamie J. Walker, Xiao Feng Li, John R. Terry, John R. Terry, Stafford L. Lightman, Kevin O'Byrne, Krasimira Tsaneva-Atanasova, Krasimira Tsaneva-Atanasova   +13 more
doaj   +1 more source

Ethanolamine plasmalogens increase luteinising hormone pulsatility and are associated with GPR61 expression in bovine gonadotrophin‐releasing hormone neurons

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Ethanolamine plasmalogens increased LH pulse frequency. GPR61 was expressed in GnRH neurons and gonadotrophs, suggesting a role in neuroendocrine regulation. Ethanolamine plasmalogens (EPls), but not choline plasmalogens (CPls), may act via GPR61 expressed in GnRH neurons in the preoptic area and in anterior pituitary gonadotrophs.
Hiroya Kadokawa, Tomoaki Kubo, Kana Kobayashi, Denis Karani Wanjiru, Yvan Bienvenu Niyonzima   +4 more
wiley   +1 more source

Sustained induction of PMOS‐like phenotype in mice exposed to letrozole in drinking water

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS; formerly polycystic ovary syndrome) is the most common endocrinopathy affecting women of reproductive age, characterized by ovarian dysfunction and hyperandrogenism, with metabolic disturbances including insulin resistance and obesity also present for 50% of PMOS patients.
Kennedy A. Stevenson, Romy Kerbus, Greg M. Anderson, Caroline Decourt   +3 more
wiley   +1 more source