Results 191 to 200 of about 40,027 (305)

Metabolic reprogramming in the post-metastatic tumor microenvironment: multi-omics insights into determinants of immunotherapy response. [PDF]

Front Immunol
Li M, Wang T, Zhang Z, Dongye Y.
europepmc   +1 more source

Renoprotective Effect of Coix lachryma‐jobi L. Seed Polysaccharides in Adenine‐Induced Chronic Renal Failure by Blocking Gut Urea Metabolism

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Dietary soluble fiber may alleviate renal damage in chronic kidney disease (CKD) by promoting intestinal urea excretion, though the underlying mechanisms remain unclear. This study investigated the digestion, fermentation, and renoprotective effects of Coix lachryma‐jobi L.
Hongmei Yin, Wanjun Liao, Yilian Huang, Qiang Hong, Na Zhang, Xiaodan Shi, Zongcai Tu, Hui Wang, Zuohua Xie, Tao Yuan   +9 more
wiley   +1 more source

Identification of a mitochondrial form of kynurenine aminotransferase/glutamine transaminase K from rat brain [PDF]

, 1995
Pari Malherbe, Daniela Alberati‐Giani, Christer Köhler, Andrea M. Cesura   +3 more
openalex   +1 more source

Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In‐Depth Review

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The main objective of this review is to explore the impact of variation within the microbiome and among genes on nutrient metabolism and argue in favor of successful evidence of individualized dietary intervention for cardiovascular disease, diabetes, and obesity.
Muhammad Tayyab Arshad, M. K. M. Ali, Farhang Hameed Awlqadr, Sammra Maqsood, Ali Ikram, Md. Sakhawot Hossain, Muhammed Adem Abdullahi, M. M. Rashed   +7 more
wiley   +1 more source

Improvement of kynurenine aminotransferase-II inhibitors guided by mimicking sulfate esters

, 2018
Gayan Jayawickrama, Alireza Nematollahi, Guanchen Sun, W. Bret Church   +3 more
openalex   +2 more sources

Spike protein-induced VSIR-ISX signaling disrupts metabolic homeostasis and promotes COVID-19-related immune dysfunction. [PDF]

Cell Biol Toxicol
Wang LT, Wang SN, Chiou SS, Chai CY, Hsu SH.   +4 more
europepmc   +1 more source

People living with HIV display increased anti-apolipoprotein A1 auto-antibodies, inflammation, and kynurenine metabolites: a case–control study [PDF]

Miguel A. Frias, Sabrina Pagano, Nasim Bararpour, Jonathan Sidibé, Festus Kamau, Vanessa Fétaud-Lapierre, Peter Hudson, Aurélien Thomas, Sandrine Lecour, Hans Strijdom, Nicolas Vuilleumier   +10 more
openalex   +1 more source

Metabolic Profiling of the EmDia Cohort by LC‐MS Reveals Empagliflozin‐Intake Associated Regulation of 1,5‐anhydroglucitol and Urate

PROTEOMICS, Volume 26, Issue 1, Page 44-56, January 2026.
ABSTRACT The EmDia trial, designed to study the effects of the sodium glucose cotransporter‐2 (SGLT2) inhibitor empagliflozin on cardiovascular comorbidities in type 2 diabetes mellitus (T2DM) patients, has been investigated for short‐term metabolic alterations by a limited set of clinical assays. To expand on this data, we report on the development of
Fabian Schmitt, Vincent ten Cate, Zlatka Fischer, Mathias Hagen, Barbara A. Steigenberger, Stefan Tenzer, Philipp S. Wild, Thierry Schmidlin   +7 more
wiley   +1 more source

The Gut Microbiota–Insulin Resistance Axis: Mechanisms, Clinical Implications, and Therapeutic Potential

FASEB BioAdvances, Volume 8, Issue 1, January 2026.
Dysbiosis‐induced alterations in microbial metabolite production promote intestinal barrier disruption and systemic inflammation, driving insulin resistance and metabolic dysfunction. Microbiota‐targeting therapies represent promising approaches to restore host metabolic health.
Mohamad Al Qassab, Nadim Chaarani, Amira Hamou, Rasha Harb, Ahmad Jradi, Mira Zeineddine, Hilda E. Ghadieh, Ziad Abi Khattar, Sami Azar, Amjad Kanaan, Frederic Harb   +10 more
wiley   +1 more source

Not Aging but Calorie Restriction Strongly Affects Protein Oxidation in Heart and Brain Mitochondria

Aging Cell, Volume 25, Issue 1, January 2026.
Our comprehensive proteomic analysis reveals that calorie restriction (CR), not aging, is the primary driver of mitochondrial protein oxidation, with striking tissue‐specific effects. While CR reduces oxidation in the heart, it exerts a dual and opposing role within the cerebrum. ABSTRACT Aging is an inevitable consequence for all organisms.
Shipan Fan, Carina Ramallo‐Guevara, Monika Frenzel, Shuichi Yanai, Sataro Goto, Michiru D. Sugawa, Norbert A. Dencher, Ansgar Poetsch   +7 more
wiley   +1 more source