Results 201 to 210 of about 40,027 (305)

Supersulfide biology and translational medicine for disease control

British Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu, Tomohiro Sawa, Motohiro Nishida, Fan‐Yan Wei, Hozumi Motohashi, Takaaki Akaike   +5 more
wiley   +1 more source

Serum Tryptophan and Kynurenine/Tryptophan Ratio as Markers of Depressive Symptoms in Chronic Obstructive Pulmonary Disease (COPD). [PDF]

Cureus
Liu A, Li Z, Yao G, Kuang Y, Guo B, Zhang R, Li H, Xie C.   +7 more
europepmc   +1 more source

Towards Automated Testing of Kynurenine for Point-of-Care Metabolomics

Dipanjan Bhattacharyya, Marcia LeVatte, David S. Wishart   +2 more
openalex   +1 more source

Redefining Roles: A Paradigm Shift in Tryptophan–Kynurenine Metabolism for Innovative Clinical Applications [PDF]

Masaru Tanaka, Ágnes Szabó, László Vécsei   +2 more
openalex   +1 more source

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

Cell Proliferation, Volume 59, Issue 1, January 2026.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng, Xin Ge, Chi Zhang, Xingye Yang, Zhengxin Yu, Min Zhang, Wen Cao, Qingtao Ni, Yang Liu, Songbing He, Yin Yuan   +10 more
wiley   +1 more source

Kynurenine enhances aryl hydrocarbon receptor signaling and expression levels of multidrug resistance genes in head and neck squamous cell carcinoma cell lines but does not change the potency of antineoplastic drugs

Gzona Bajraktari‐Sylejmani, Marlene Piribauer, Sven Groessl, Patrick Bernhard, Gerhard Dyckhoff, Rolf Warta, Christel Herold‐Mende, Dirk Theile, Johanna Weiß   +8 more
openalex   +1 more source

Dendritic Cells in the Gastrointestinal System: Division of Labor, Plasticity, and Niche‐Specific Adaptation

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT The intestinal immune system is constantly challenged to distinguish between innocuous dietary antigens, commensal microbiota and intestinal self‐antigens (self‐Ags) versus harmful pathogens and malignant cells. It resides in the intestinal wall itself, Peyer's patches (PPs) and the draining lymph nodes (LNs).
Yixuan D. Zhou, Macy R. Komnick, Daria Esterházy   +2 more
wiley   +1 more source

Stress Nutrition in Aquatic Animals: From Definition to Practice

Reviews in Aquaculture, Volume 18, Issue 1, January 2026.
ABSTRACT Aquaculture faces numerous challenges, with stress being one of the major issues that lead to growth loss, metabolic disorders, weakened immunity, redox imbalance, and organ damage in aquatic animals. Nutritional intervention is one of the effective strategies to address these problems. Traditional research has primarily focused on the impacts
Jian Zhang, Qianwen Ding, Ruobing Lou, Yuanpei Zhang, Yuanyuan Yao, Yalin Yang, Zhen Zhang, Chao Ran, Zhigang Zhou   +8 more
wiley   +1 more source

Leaf beetles employ tryptophan to detoxify the chemical defenses of poplar trees. [PDF]

Proc Natl Acad Sci U S A
Peng X, Reichelt M, Baños-Quintana AP, Rothe B, Feistel F, Kaltenpoth M, Gershenzon J, Unsicker SB.   +7 more
europepmc   +1 more source

Kynurenine System and Multiple Sclerosis, Pathomechanism and Drug Targets with An Emphasis on Laquinimod

, 2018
Zsófia Majláth, Ádám Annus, László Vécsei   +2 more
openalex   +2 more sources