Results 221 to 230 of about 34,126 (294)

Altitude‐Associated Divergence of the Gut Microbiome in Endangered Forest Musk Deer: Evidence From Integrated Metagenomics, Metabolomics, and Culturomics

Evolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT High‐altitude environments expose mammals and their gut symbionts to multifaceted stressors—hypoxia, cold, and intense UV radiation. Whether gut microbial communities undergo compositional restructuring in response to these stressors, and whether such restructuring carries translational value for captive conservation, remain unresolved ...
Feiyun Huang, Zexiu Zhang, Yanni Zhao, Sen Ye, Maoyuan Gan, Xuxin Li, Yele Zhang, Lei Chen, Yushuo Zhang, Lingxi Chen, Ting Wang, Jinming Huang, Xiuyue Zhang   +12 more
wiley   +1 more source

Untargeted and Targeted Cerebrospinal Fluid Neurometabolomics via Chromatography-Mass Spectrometry-Based Methods. [PDF]

Molecules
Pautova AK.
europepmc   +1 more source

Integrated Network Pharmacology and Machine Learning to Reveal the Mechanisms of Schisandrin A Against Triple‐Negative Breast Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT This study aimed to elucidate the mechanism of action of Schisandrin A in the intervention of triple‐negative breast cancer (TNBC). Through the application of network pharmacology and the integration of targets from multiple databases, the research identified 128 overlapping targets between Schisandrin A and TNBC.
Meng Xu, Yingchun Zhang, Rubing Mei, Tingting Xue, Hongning Cai, Yu Zhou, Jianfang Guo   +6 more
wiley   +1 more source

Gut‑brain axis in anesthesia and critical illness: Molecular crosstalk and its impact on delirium and outcome (Review). [PDF]

Int J Mol Med
Ma X, Zhao Y.
europepmc   +1 more source

Hierarchical Disruption of the Tryptophan–Melatonin Axis Contributes to Glioma Progression Through AKT/ERK/STAT3 Signalling

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Melatonin signalling, mediated by membrane receptors and tightly regulated biosynthetic enzymes, is a key component of circadian and neuroendocrine control in the brain. However, whether the tryptophan–melatonin axis remains hierarchically intact during glioma progression and how its disruption affects downstream signalling remain unclear.
Bo Tan, Suqiu Yao, Shuangyin He, Tao Chen, Han Chen, Wenfu Yang, Xiyuan Tang, Tingting Xu, Jiajie Zhang, Xiaohong Yin, Ying Chen, Peng Song   +11 more
wiley   +1 more source

Physical Activity, Metabolic Dysfunction, and the Kynurenine Pathway in Endometriosis and Polycystic Ovary Syndrome: A Literature Review. [PDF]

Biomolecules
Varga N, Kis-György R, Ajkay-Donáth L, Tapody ZI, Vágvölgyi-Sümegi E, Körtési T, Nagy-Grócz G.   +6 more
europepmc   +1 more source

Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect

Journal of Child Psychology and Psychiatry, Volume 67, Issue 6, Page 816-831, June 2026.
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson, Hanna R. Wright, Jorden E. Jacinto Schreeder, Joel T. Nigg, Elinor L. Sullivan   +4 more
wiley   +1 more source

Serum inflammatory cytokines in the progression of depression. [PDF]

Front Immunol
Feng Q, Yuan Z, An Q, Wang K, Liu X.
europepmc   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Persons With Multiple Sclerosis Reveal Distinct Kynurenine Pathway Metabolite Patterns: A Multinational Cross-Sectional Study. [PDF]

Neurol Neuroimmunol Neuroinflamm
Kupjetz M, Langeskov-Christensen M, Riemenschneider M, Inerle S, Ligges U, Gaemelke T, Patt N, Bansi J, Gonzenbach RR, Reuter M, Rosenberger F, Meyer T, McCann A, Ueland PM, Eskildsen SF, Emil Nygaard MK, Joisten N, Hvid L, Dalgas U, Zimmer P.   +19 more
europepmc   +1 more source