Results 241 to 250 of about 34,126 (294)

Anchoring ALS Prognosis: Neurofilament Light Chain Outperforms Inflammatory, Metabolic, and CNS Barrier Biomarkers in the METABALS Cohort. [PDF]

open access: yesMol Neurobiol
Alarcan H   +16 more
europepmc   +1 more source

Modulation of Enzyme Activity in the Kynurenine Pathway by Kynurenine Monooxygenase Inhibition [PDF]

open access: yesFrontiers in Molecular Biosciences, 2019
The kynurenine pathway is the major route for tryptophan metabolism in mammals. Several of the metabolites in the kynurenine pathway, however, are potentially toxic, particularly 3-hydroxykynurenine, 3-hydroxyanthranilic acid, and quinolinic acid. Quinolinic acid (QUIN) is an excitotoxic agonist at the NMDA receptor, and has been shown to be elevated ...
Robert S Phillips, J Phillip Bowen
exaly   +5 more sources

Kynurenine metabolism in health and disease

open access: yesAmino Acids, 2010
Kynurenine is a small molecule derived from tryptophan when this amino acid is metabolised via the kynurenine pathway. The biological activity of kynurenine and its metabolites (kynurenines) is well recognised.
Ewa M Paleolog, , Paleolog Ewa M
exaly   +2 more sources

Home - About - Disclaimer - Privacy