MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia +4 more
wiley +1 more source
Mutual information minimization enhances noise robustness and induces fault containment in functionally differentiated recurrent neural networks. [PDF]
Tomoda Y, Yamaguti Y.
europepmc +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Mechanical transmission of impulsive instrument-assisted spinal manipulation: contact-site-dependent biomechanical coupling in the <i>in vivo</i> human lumbar spine. [PDF]
Colloca CJ +3 more
europepmc +1 more source
Aptamer-Functionalized Liposomes for Targeted Delivery of Anticancer Drugs in Lung Cancer. [PDF]
Leitão D +4 more
europepmc +1 more source
Word frequency modulates the use of initial and final morpheme positional probabilities during Chinese sentence reading in L2 learners: an eye-tracking study. [PDF]
Song T, Zhang T.
europepmc +1 more source
Translation direction and word familiarity in word translation: an fNIRS study of intermediate Japanese learners of English. [PDF]
Kawai W +5 more
europepmc +1 more source
Spinal granulocytic sarcoma with both extradural and intradural involvement: a case report. [PDF]
Zhang J +4 more
europepmc +1 more source
A forward genetics platform for papillomavirus research. [PDF]
Takeo Y, Hirsch SR, DiMaio D.
europepmc +1 more source

