Results 1 to 10 of about 2,614 (160)

SBP-Box Transcription Factor JcSPL9 Regulates Both Seed Yield and Oil Content in the Biofuel Plant Jatropha curcas. [PDF]

Plant Biotechnol J
ABSTRACT Jatropha curcas is a promising feedstock for biodiesel and bio‐jet fuels production; however, its seed yield is constrained by limited inflorescences. SPL9 is a member of the SBP‐box gene family that promotes the juvenile‐to‐adult phase transition.
Tang M, Bai X, Xia Y, Huang P, Xu ZF.
europepmc   +2 more sources

Improving Lyme disease testing with data driven test design in pediatrics [PDF]

Journal of Pathology Informatics, 2023
Diagnostic advances have not kept pace with the expansion of Lyme disease caused by Borrelia burgdorferi and transmitted by ticks. Lyme disease clinical manifestations can overlap with many other diagnoses making Lyme disease a critical part of many ...
Mahmoud Elkhadrawi, Oscar Lopez-Nunez, Murat Akcakaya, Sarah E. Wheeler   +3 more
doaj   +2 more sources

Ligand-controlled regiodivergent and enantioselective C–H cyanation of secondary amines [PDF]

Nature Communications
Aliphatic amines, such as N,N-dialkyl secondary amines, represent important scaffolds in bioactive molecules, driving significant interest in their regio- and stereoselective C–H functionalisation.
Yang-Jie Mao, Xiahe Chen, Huan-Le Li, Qi Pan, Kun Zhou, Zhen-Yuan Xu, Yun-Fang Yang, Shao-Jie Lou, Dan-Qian Xu   +8 more
doaj   +2 more sources

A Gcn4p Homolog Is Essential for the Induction of a Ribosomal Protein L41 Variant Responsible for Cycloheximide Resistance in the Yeast Candida maltosa [PDF]

Journal of Biological Chemistry, 2004
Cycloheximide (CYH) resistance in the yeast Candida maltosa is based on the inducible expression of genes encoding a variant of ribosomal protein L41-Q, with glutamine at position 56 instead of the proline found in normal L41. The promoter of L41-Q2a, one of the L41-Q gene alleles encoding L41-Q, has an element similar to the Gcn4p-responsive element ...
Ryouichi Fukuda, Akinori Ohta, Kozo Ochi   +2 more
exaly   +4 more sources

Gene structure of the carp fish ribosomal protein L41: seasonally regulated expression

Biochemical and Biophysical Research Communications, 2002
The seasonal acclimatization of the carp fish demands physiological compensatory responses. The process involves profound nucleolar adjustments and remarkable changes in rRNA synthesis, which affect ribosomal biogenesis. We have documented that protein kinase CK2, whose activity is related to ribosomal protein L41 and the regulation of rRNA synthesis ...
Alfredo Molina, Manuel Krauskopf, Marco Alvarez   +2 more
exaly   +6 more sources

Drastic alteration of cycloheximide sensitivity by substitution of one amino acid in the L41 ribosomal protein of yeasts [PDF]

Journal of Bacteriology, 1992
Cycloheximide is one of the antibiotics that inhibit protein synthesis in most eukaryotic cells. We have found that a yeast, Candida maltosa, is resistant to the drug because it possesses a cycloheximide-resistant ribosome, and we have isolated the gene responsible for this.
S Murao, I Shibuya
exaly   +3 more sources

Comparing Pediatric Dermatology Research Funded by the US National Institutes of Health (NIH) With the US Skin Disease Burden in Patients Under 20 Years Old. [PDF]

Pediatr Dermatol
ABSTRACT Background Disease burden, measured by disability‐adjusted life years (DALYs), is a helpful metric to guide research funding priorities. Pediatric dermatologic conditions significantly contribute to DALYs, yet it is unclear whether NIH funding reflects this burden.
Mackenzie E, Amancharla N, Casagrande S, Ayyaz W, Tchack M, Musolff N, Rao B.   +6 more
europepmc   +2 more sources

A genetic transformation system for the heterotrophic diatom Nitzschia putrida (Bacillariophyceae). [PDF]

J Phycol
Abstract Diatoms are important primary producers in aquatic ecosystems. Most of them are photoautotrophs and have evolved to thrive under diverse environmental conditions from the poles to the tropics. However, some diatom species such as Nitzschia putrida have lost photosynthesis and have therefore become free‐living secondary heterotrophs.
Deng L, Li Y, Tanizawa Y, Nakamura Y, Kamikawa R, Hopes A, Mock T.   +6 more
europepmc   +2 more sources

Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ25–35 peptide administration in mice [PDF]

European Neuropsychopharmacology, 2015
Dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) and cdc2-like kinases (CLKs) are implicated in the onset and progression of Down syndrome (DS) and Alzheimer's disease (AD). DYRK1A has emerged as a possible link between amyloid-β (Aβ) and Tau, the major pathological proteins in AD.
Tangui Maurice, Laurent Givalois, François Carreaux   +2 more
exaly   +4 more sources

The Highly Basic Ribosomal Protein L41 Interacts with the β Subunit of Protein Kinase CKII and Stimulates Phosphorylation of DNA Topoisomerase IIα by CKII

Biochemical and Biophysical Research Communications, 1997
Protein kinase CKII (CKII) is a heterotetramer composed of two catalytic (alpha or alpha') and two regulatory (beta) subunits. Using the yeast two-hybrid system, we have identified the highly basic, ribosomal protein L41 as a cellular protein capable of interacting with the beta subunit of CKII.
Young-Seuk Bae, D R Marshak, Y S Bae
exaly   +3 more sources