Results 161 to 170 of about 96,178 (343)

Loganin, an Iridoid Glycoside, Alleviates Paclitaxel‐Induced Skeletal Muscle Toxicity by Enhancing Mitochondrial Function, Boosting Antioxidant Defenses, and Reducing Cellular Senescence

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondrial dysfunction and energy imbalance caused by chemotherapy are key contributors to skeletal muscle atrophy, which severely impacts the quality of life in cancer patients. Paclitaxel, a commonly used chemotherapeutic agent, is known to promote muscle wasting and cellular senescence, largely by impairing mitochondrial function.
Yu‐Fan Chuang   +6 more
wiley   +1 more source

Embryonic and post-embryonic utilization and subcellular localization of the nuclear receptor SpSHR2 in the sea urchin [PDF]

open access: yes, 1998
SpSHR2 (Strongylocentrotus purpuratus steroid hormone receptor 2) is a nuclear receptor, encoded by a maternal RNA in the sea urchin embryo. These maternal SpSHR2 transcripts, which are present in all cells, persist until the blastula stage and then are ...
Flytzanis, Constantin N.   +2 more
core  

Simian virus 40 induces lamin A/C fluctuations and nuclear envelope deformation during cell entry [PDF]

open access: hybrid, 2011
Veronika Butin‐Israeli   +6 more
openalex   +1 more source

Hypoxia‐Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β‐Catenin Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu   +6 more
wiley   +1 more source

Journal of African Christian Biography: v. 1, no. 1 [PDF]

open access: yes, 2016
A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1.
Belcher, Wendy Laura   +2 more
core  

The role of nuclear lamin B1 in cell proliferation and senescence [PDF]

open access: diamond, 2011
Takeshi Shimi   +9 more
openalex   +1 more source

Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling   +6 more
wiley   +1 more source

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

open access: yesNature, 2003
M. Eriksson   +17 more
semanticscholar   +1 more source

Computational Characterization of the Role of LEM2/LaminA Interactions on the Stability of BAF‐Dimer Using Molecular Simulations

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The effect of the presence of the BAF‐binding LEM‐domain and LaminA Ig‐fold on the stability of the BAF dimer was studied qualitatively using non‐equilibrium pull simulations and quantitatively through the calculation of the potential of mean force profile along BAF–BAF separation distance.
Aswin Vinod Muthachikavil   +2 more
wiley   +1 more source

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