Results 51 to 60 of about 129 (128)

Prediction and prognostic role of left ventricular systolic dysfunction in family screening for dilated cardiomyopathy and non‐dilated left ventricular cardiomyopathy

European Journal of Heart Failure, EarlyView.
Aims The prognostic significance of detecting left ventricular (LV) systolic dysfunction during family screening programmes (FSPs) in relatives of probands affected by dilated (DCM) and non‐dilated left ventricular (NDLVC) cardiomyopathies remain unclear.
Eva Del Mestre, Alessia Paldino, Carola Pio Loco Detto Gava, Ilaria Gandin, Marta Gigli, Davide Stolfo, Martina Setti, Giovanni Maria Severini, Beatrice Spedicati, Stefania Lenarduzzi, Giorgia Girotto, Alessandro Folgheraiter, Jacopo Giulio Rizzi, Renata Korcova, Luisa Mestroni, Marco Merlo, Matteo Dal Ferro, Gianfranco Sinagra   +17 more
wiley   +1 more source

Strange Laminates

Mathematical Methods in the Applied Sciences, 2012
Laminates made of composite anisotropic layers have a large varieties of different possible elastic responses. Still remaining in the classical field of linear elasticity, it is possible to obtain, with laminates, elastic behaviors that are very strange and completely unusual not only for classical materials, like metallic alloys, but also for the same
openaire   +3 more sources

Integrated role of cardiac magnetic resonance and genetics in predicting left ventricular reverse remodelling in dilated and non‐dilated cardiomyopathy

European Journal of Heart Failure, EarlyView.
An integrated approach including late gadolinium enhancement data and genetics to predict left ventricular reverse remodelling in patients with dilated and non‐dilated left ventricular cardiomyopathy. DSP, desmoplakin; FLNC, filamin C; LMNA, lamin A/C; LVRR, left ventricular reverse remodelling; LGE, late gadolinium enhancement; MVA, major ventricular ...
Martina Setti, Manuela Iseppi, Job A.J. Verdonschot, Jacopo G. Rizzi, Alessia Paldino, Carola Pio Loco Detto Gava, Giulia Barbati, Matteo Dal Ferro, Max F.G.H.M. Venner, Anne G. Raafs, Marta Gigli, Davide Stolfo, Antonio De Luca, Giulia De Angelis, Teresa M. Capovilla, Sharon Graw, Flavio L. Ribichini, Matthew Taylor, Luisa Mestroni, Stephane R.B. Heymans, Gianfranco Sinagra, Marco Merlo   +21 more
wiley   +1 more source

Age‐related penetrance of phospholamban p.Arg14del cardiomyopathy

European Journal of Heart Failure, EarlyView.
Age‐related penetrance of phospholamban (PLN) p.Arg14del cardiomyopathy. ECG, electrocardiogram; ICD, implantable cardioverter‐defibrillator; LVAD, left ventricular assist device; LVEF, left ventricular ejection fraction; MRI, magnetic resonance imaging; PVC, premature ventricular contraction; SCD, sudden cardiac death; VF, ventricular fibrillation; VT,
Tom E. Verstraelen, Freyja H.M. van Lint, Remco de Brouwer, Virginnio M. Proost, Esmee van Drie, Laurens P. Bosman, Lotte Weverink, Karim Taha, Thais Bueren, Aeilko H. Zwinderman, Cathelijne Dickhoff, Toon Oomen, Bas A. Schoonderwoerd, Tjeerd Germans, Arjan C. Houweling, Juan R. Gimeno‐Blanes, Folkert W. Asselbergs, Paul A. van der Zwaag, Anneline S.J.M. te Riele, Rudolf A. de Boer, Maarten P. van den Berg, J. Peter van Tintelen, Arthur A.M. Wilde   +22 more
wiley   +1 more source

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

Exploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao, Xiaoqing Zhang, Jiamei Sun, Hongyan Dong, Xin Han, Qiao Yang, Roufen Chen, Liteng Shen, Lei Xu, Lu Wang, Bo Zhu, Dongxin Tang, Shuosheng Zhang, Keda Lu, Mengyun Peng, Gang Cao   +15 more
wiley   +1 more source

Dendranthema oreastrum (Hance) Y.Ling Attenuates Oxidative Stress and Airway Inflammation in a Murine Model of Lipopolysaccharide‐Induced Acute Lung Injury

Environmental Toxicology, EarlyView.
ABSTRACT We examined the antioxidant and anti‐inflammatory effects of the methanolic extract of Dendranthema oreastrum (Hance) Y.Ling, commonly known as “Gu‐Jeol‐Cho” in Korea and widely found across East Asia, using an LPS‐induced acute lung injury (ALI) mouse model and TNF‐α‐stimulated NCI‐H292 cells.
Ji‐Hye Ha, Ba‐Wool Lee, Da‐Hye Yi, Seong‐Hun Jeong, Ju‐Hong Kim, Hyun‐Jae Jang, Ju Hwan Jeong, Ji‐Young Park, Hyung Jae Jeong, Hyung‐Jun Kwon, Young‐Bae Ryu, In‐Chul Lee   +11 more
wiley   +1 more source

Myonuclear alterations associated with exercise are independent of age in humans

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Structural and mechanical properties of myonuclei in trained young and aged individuals. In skeletal muscle fibres from trained individuals, myonuclei are more spherical, have greater lamin A and are stiffer compared to untrained counterparts.
E. Battey, J. A. Ross, A. Hoang, D. G. S. Wilson, Y. Han, Y. Levy, R. D. Pollock, M. Kalakoutis, J. N. Pugh, G. L. Close, G. M. Ellison‐Hughes, N. R. Lazarus, T. Iskratsch, S. D. R. Harridge, J. Ochala, M. J. Stroud   +15 more
wiley   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

VIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma, Junxin Chen, Yuan Du, Zhihao Cao, Weizhi Ji, Yuyu Niu, Zebin Yang   +6 more
wiley   +1 more source

The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells

FASEB BioAdvances, EarlyView.
The SUV39 family members are well known for methylating the Lysine 9 of the histone H3 (H3K9) in order to compact the chromatin and contributing to gene repression. We describe their active role in proliferating and differentiating muscle stem cells, how they prevent from inflammation and fibrosis during muscle regeneration and the future avenues ...
Pauline Garcia, Slimane Ait‐Si‐Ali, Fabien Le Grand   +2 more
wiley   +1 more source

Ethnic Polarization and Ownership Decision in Cross‐Border Acquisitions: The Case of Emerging Market Multinational Enterprises

British Journal of Management, EarlyView.
Abstract Ethnic issues have been creating complex sociopolitical realities and grand challenges for economic activities in many countries, yet much less is known about their micro‐level effects on international business. This study explores the impact of ethnic polarization in target countries on equity ownership in cross‐border acquisitions (CBAs) by ...
Jianhong Zhang, Jiangang Jiang
wiley   +1 more source