Results 91 to 100 of about 4,141,686 (289)

Test-Time Augmentation for Cross-Domain Leukocyte Classification via OOD Filtering and Self-Ensembling

open access: yesJournal of Imaging
Domain shift poses a major challenge in many Machine Learning applications due to variations in data acquisition protocols, particularly in the medical field.
Lorenzo Putzu   +2 more
doaj   +1 more source

Late-time Instability for UPML and Periodic Boundary in Elongated Multilayer Thin Plate Simulations [PDF]

open access: yesRadioengineering, 2019
In this article, we examine the late-time instability properties of hybrid boundary conditions in the discontinuous Galerkin time-domain (DGTD) simulations of an elongated multilayer thin plate.
H. P. Li, Y. Wang, Q. S. Cao
doaj  

Antena Spiral-dipole untuk Ground Penetrating Radar (GPR)

open access: yesJurnal Elektronika dan Telekomunikasi, 2016
GPR (Ground Penetrating Radar) merupakan divais yang berguna untuk proses pendeteksian objek yang terkubur di bawah permukaan tanah hingga kedalaman tertentu, tanpa perlu dilakukan penggalian tanah. Pada penelitian ini dilakukan perancangan, simulasi dan
Yuyu Wahyu   +3 more
doaj   +1 more source

Accumulation of endogenous LITAF in aggresomes. [PDF]

open access: yesPLoS ONE, 2012
LITAF is a 161 amino acid cellular protein which includes a proline rich N-terminus and a conserved C-terminal domain known as the simple-like domain.
Heather E Eaton   +3 more
doaj   +1 more source

In planta localisation patterns of MADS domain proteins during floral development in Arabidopsis thaliana [PDF]

open access: yes, 2009
Background: MADS domain transcription factors play important roles in various developmental processes in flowering plants. Members of this family play a prominent role in the transition to flowering and the specification of floral organ identity. Several
Angenent, G.C.   +6 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Continuity of outcome assessment throughout the lifecycle of surgical research: mapping core outcome domains measured in early phase and late phase studies

open access: yesBMC Surgery
Background Consistent outcome assessment in surgical research, from early phase studies (during introduction and refinement of new procedures) to late phase studies (to establish comparative effectiveness) needs improvement to ensure efficient and safe ...
Christin Hoffmann   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Anti-bis(monoacylglycero)phosphate antibody accumulates acetylated LDL-derived cholesterol in cultured macrophages

open access: yesJournal of Lipid Research, 2007
Bis(monoacylglycero)phosphate (BMP), also called lysobisphosphatidic acid, is a phospholipid highly enriched in the internal membranes of multivesicular late endosomes, in which it forms specialized lipid domains.
Isabelle Delton-Vandenbroucke   +6 more
doaj   +1 more source

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