Results 101 to 110 of about 4,141,686 (289)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Low Delay Noise Reduction and Dereverberation for Hearing Aids
EURASIP Journal on Advances in Signal Processing, 2009 A new system for single-channel speech enhancement is proposed which achieves a joint suppression of late reverberant speech and background noise with a low signal delay and low computational complexity.
Heinrich W. Löllmann +1 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
PLoS Pathogens, 2014 Endosomal sorting complex required for transport (ESCRT) machinery supports the efficient budding of Marburg virus (MARV) and many other enveloped viruses. Interaction between components of the ESCRT machinery and viral proteins is predominantly mediated
Olga Dolnik +5 more
doaj +1 more source
Domain boundary engineering [PDF]
We review the idea that domain boundaries, rather than domains, can carry information and act as memory devices. Domains are bulk objects; their large response to changing external fields is related to their change in volume, which implies the movement ...
Salje, E. K. H., Zhang, H. L.
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Is Resistance-to-Interference Domain-General or Domain-Specific? A multi-paradigm investigation
, 2023 The research conducted in this multi-paradigm investigation aimed to address the question of whether resistance-to-interference (RI) processes are domain-general or domain-specific.
Gregoire, Coline
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Research Perspectives on the Public Domain [PDF]
, 2014 This document presents an edited transcript of the one-day event, ‘Research Perspectives on the Public Domain’, held at the University of Glasgow on 11thOctober, 2013.
Erickson, Kristofer, Kretschmer, Martin
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source