Results 111 to 120 of about 672,964 (288)

A domain-based late-fusion for disaster image retrieval from social media [PDF]

open access: yes, 2017
We introduce a domain-speci c and late-fusion algorithm to cope with the challenge raised in The MediaEval 2017 Multimedia Satel- lite Task. Several known techniques are integrated based on domain- speci c criteria such as late fusion, tuning, ensemble ...
Dao, Minh-Son   +4 more
core  

Structure-function study of mammalian Munc18-1 and C. elegans UNC-18 implicates domain 3b in the regulation of exocytosis [PDF]

open access: yes, 2011
This work was supported by grants from the Wellcome Trust and BBSRC. GRP was supported by a Wellcome Trust Prize Studentship. The C. elegans strain used in this work was provided by the Caenorhabditis Genetics Center, which is funded by the National ...
Haynes, Lee P.   +32 more
core   +1 more source

BIOSTRATIGRAPHIC STUDY OF THE ILAM AND GURPI FORMATIONS BASED ON PLANKTONIC FORAMINIFERA IN SE OF SHIRAZ, IRAN [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2002
The study of planktonic foraminifera of the Ilam and Gurpi formations at Sarvestan area (SE of Shiraz) enables me to find the most standard biozones defined in mediterranean regions, especially Tethysian domain. Seven biozones were determined. Biozones I
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

H3 K36 Methylation Helps Determine the Timing of Cdc45 Association with Replication Origins [PDF]

open access: yes, 2009
BackgroundReplication origins fire at different times during S-phase. Such timing is determined by the chromosomal context, which includes the activity of nearby genes, telomeric position effects and chromatin structure, such as the acetylation state of ...
Mariotti, F.R.   +11 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Functional characterization of the MENTAL domain [PDF]

open access: yes, 2005
International audienceHuman metastatic lymph node (MLN) 64 is composed of two conserved regions. The amino terminus contains a conserved membrane-spanning MENTAL (MLN64 NH(2)-terminal) domain shared with an unique protein called MENTHO (MLN64 NH(2 ...
Latchumanan, V.   +17 more
core   +1 more source

The neural signature of self-concept development in adolescence: The role of domain and valence distinctions

open access: yesDevelopmental Cognitive Neuroscience, 2018
Neuroimaging studies in adults showed that cortical midline regions including medial prefrontal cortex (mPFC) and posterior parietal cortex (PPC) are important in self-evaluations.
R. van der Cruijsen   +3 more
doaj   +1 more source

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