Results 101 to 110 of about 2,855 (207)

The relationships of markers of cholesterol homeostasis with carotid intima-media thickness.

open access: yesPLoS ONE, 2010
BackgroundThe relationship of cholesterol homeostasis and carotid intima-media thickness (cIMT) is unknown. To address this, we assessed markers of cholesterol homeostasis (serum plant sterols and cholesterol precursor concentrations as surrogate ...
Oliver Weingärtner   +12 more
doaj   +1 more source

A detailed genome-wide reconstruction of mouse metabolism based on human Recon 1 [PDF]

open access: yes, 2010
Background Well-curated and validated network reconstructions are extremely valuable tools in systems biology. Detailed metabolic reconstructions of mammals have recently emerged, including human reconstructions.
Martin I Sigurdsson   +4 more
core   +1 more source

Sterol composition of three marine sponge species from the genus Cinachyrella [PDF]

open access: yes, 1992
The hitherto undescribed sterol composition of three marine sponge species belonging to the genus #Cynachyrella$ are reported : #C. alloclada$ and #C. kukenthali$ from the Senegalese coast, at two different depths, and C. aff.
Barnathan, J.   +7 more
core   +1 more source

Biosynthesis of Δ7-cholesten-3Β-ol, Δ5,7-cholestadien-3Β-ol, and Δ5-cholesten-3Β-ol by guinea pig intestinal mucosa in vitro

open access: yesJournal of Lipid Research, 1966
Methods were developed for the separation and determination of the various 27-carbon sterols of intestinal mucosa by means of thin-layer chromatography.
Robert K. Ockner, Leonard Laster
doaj   +1 more source

Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain

open access: yesJournal of Lipid Research, 2002
Cholesterol is implicated to play a role in Alzheimer disease pathology. Therefore, the concentrations of cholesterol, its precursors, and its degradation products in brain homogenates of aging wild-type and β-amyloid precursor protein transgenic mice ...
Dieter Lütjohann   +8 more
doaj   +1 more source

Effects of vitamin D on serum lipid profile in patients with type 2 diabetes: A meta-analysis of randomized controlled trials [PDF]

open access: yes, 2016
Background & aims The effect of vitamin D on lipid profile in type 2 diabetic patients is controversial. This meta-analysis aimed to assess the effect of vitamin D on serum total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL), and ...
Barani, Afshin.   +2 more
core   +1 more source

Accumulation of cholesterol precursors and plant sterols in human stenotic aortic valves

open access: yesJournal of Lipid Research, 2008
The pathogenesis of aortic valve stenosis (AS) is characterized by the accumulation of LDL-derived cholesterol in the diseased valves. Since LDL particles also contain plant sterols, we investigated whether plant sterols accumulate in aortic valve ...
Satu Helske   +8 more
doaj   +1 more source

Fasting reduces plasma proprotein convertase, subtilisin/kexin type 9 and cholesterol biosynthesis in humans

open access: yesJournal of Lipid Research, 2010
Proprotein convertase, subtilisin/kexin type 9 (PCSK9), a key regulator of plasma LDL-cholesterol (LDL-c) and cardiovascular risk, is produced in liver and secreted into plasma where it binds hepatic LDL receptors (LDLR), leading to their degradation ...
Jeffrey D. Browning, Jay D. Horton
doaj   +1 more source

Vitamin D in plants: a review of occurrence, analysis, and biosynthesis. [PDF]

open access: yes, 2013
The major function of vitamin D in vertebrates is maintenance of calcium homeostasis, but vitamin D insufficiency has also been linked to an increased risk of hypertension, autoimmune diseases, diabetes and cancer. Therefore, there is a growing awareness
Jakobsen, Jette, Jäpelt, Rie Bak
core   +2 more sources

Phytosterolemia on the island of Kosrae

open access: yesJournal of Lipid Research, 2004
Screening of 932 adults on the Pacific island of Kosrae for plasma plant sterol levels disclosed three subjects, two of them asymptomatic, with phytosterolemia. Sequencing the ATP binding cassette subfamily G member 8 (ABCG8) gene revealed a novel exon 2
Ephraim Sehayek   +10 more
doaj   +1 more source

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