Results 111 to 120 of about 2,855 (207)

Automated pathway and reaction prediction facilitates in silico identification of unknown metabolites in human cohort studies [PDF]

, 2017
Identification of metabolites in non-targeted metabolomics continues to be a bottleneck in metabolomics studies in large human cohorts. Unidentified metabolites frequently emerge in the results of association studies linking metabolite levels to, for ...
Agakov, Ahluwalia, Allen, Anne M. Evans, Baldassarre, Beger, Borodulin, Boudonck, Breitling, Carlsson, Chen, Creek, Evans, Felix Agakov, Frainay, Fuhrer, Gabi Kastenmüller, Grapov, Helen C. Looker, Helen M. Colhoun, Höllering, Jan D. Quell, Jan Krumsiek, Kanehisa, Kim, Krumsiek, Krumsiek, Lacroix, Leif C. Groop, Marco Colombo, Orchard, Paul McKeigue, Pearson, R Core Team, Robert Mohney, Romero, Ruttkies, Schaefer, Shin, Sumner, Thiele, Ulf de Faire, van Buuren, van der Hooft, van Helden, Veikko Salomaa, Werner, Werner Römisch-Margl, Yin   +48 more
core   +1 more source

Separation and Determination of Some of the Main Cholesterol-Related Compounds in Blood by Gas Chromatography-Mass Spectrometry (Selected Ion Monitoring Mode)

Separations, 2018
Oxysterols are metabolites produced in the first step of cholesterol metabolism, which is related to neurodegenerative disorder. They can be detected by testing blood, plasma, serum, or cerebrospinal fluid.
Lucia Valverde-Som, Alegría Carrasco-Pancorbo, Saleta Sierra, Soraya Santana, Cristina Ruiz-Samblás, Natalia Navas, Javier S. Burgos, Luis Cuadros-Rodríguez   +7 more
doaj   +1 more source

The interrelations between PCSK9 metabolism and cholesterol synthesis and absorption

Journal of Lipid Research, 2019
Very few studies have investigated the interrelations between proprotein convertase subtilisin/kexin type 9 (PCSK9) metabolism, cholesterol synthesis, and cholesterol absorption.
Günther Silbernagel, Lars K. Steiner, Tim Hollstein, Günter Fauler, Hubert Scharnagl, Tatjana Stojakovic, Friederike Schumann, Bediha Bölükbasi, Winfried März, Elisabeth Steinhagen-Thiessen, Ulrich Laufs, Ursula Kassner   +11 more
doaj   +1 more source

Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes [PDF]

, 2018
Previous studies have indicated that the early steps in the isoprenoid/cholesterol biosynthetic pathway occur in peroxisomes. However, the role of peroxisomes in cholesterol biosynthesis has recently been questioned in several reports concluding that ...
Brunengraber, Henri, Duan, Xueying, Kasumov, Takhar, Kelleher, Joanne, Kovacs, Werner, Krisans, Skaidrite, Shackelford, Janis, Tape, Khanichi   +7 more
core  

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. [PDF]

, 2019
Tumor subtype-specific metabolic reprogrammers could serve as targets of therapeutic intervention. Here we show that triple-negative breast cancer (TNBC) exhibits a hyper-activated cholesterol-biosynthesis program that is strongly linked to nuclear ...
Bold, Richard J, Borowsky, Alexander D, Cai, Demin, Chen, Hong-Wu, Chen, Xinbin, Evans, Ronald M, Fiehn, Oliver, Gao, Bei, Huang, Zenghong, Jiang, Yuqian, Kung, Hsing-Jien, Lam, Kit S, Lara, Primo N, Li, Jian Jian, Li, Jin, To, Ka-Fai, Wang, Junjian, Wu, Feng, Xu, Jianzhen, Zhao, Ruqian, Zou, Hongye, Zou, June X   +21 more
core  

Methods in lipid analysis [PDF]

, 1982
Procedure for the following are given Total lipid extraction and purification Free fatty acid in crude and refined oils Separation of lipids by thin-layer chromatography Gas liquid chromatography of fatty acids and sterols Separation of neutral ...
Kanazawa, Akio
core  

Sterol metabolism. 6. The interconversion of cholesterol, 7-dehydrocholesterol and lathosterol in the rat [PDF]

Biochemical Journal, 1961
E I, MERCER, J, GLOVER
openaire   +2 more sources

Cholesterol Absorption and Synthesis Markers: Risk for Cardiovascular Diseases? [PDF]

J Atheroscler Thromb, 2023
Minami M.
europepmc   +1 more source

Diagnostic Fragmentations of Animal and Fungal Sterols/Stanols Obtained by APCI-Tandem Mass Spectrometry: A Route Towards Unknown Free Sterol Identification. [PDF]

Metabolites
Cinquepalmi V, Losito I, Castellaneta A, Calvano CD, Cataldi TRI.   +4 more
europepmc   +1 more source

First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods [PDF]

, 2019
et al,, Lütjohann, Dieter, Ostlund, Richard E   +2 more
core   +1 more source