Results 31 to 40 of about 13,685 (176)

Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]

, 2009
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni, Blackburn, Clare, Brand, Janko, Brinkmann, Volker, Hoffmann, Kirstin, Lippuner, Christoph, Paape, Daniel, Paterou, Athina, Richardson, Melville, Smith, Andrew   +9 more
core   +1 more source

Phlebotomine fauna (Diptera: Psychodidae) of an American cutaneous leishmaniasis endemic area in the state of Mato Grosso do Sul, Brazil [PDF]

, 2009
The occurrence of an outbreak of cutaneous leishmaniasis associated with Leishmania (Leishmania) amazonensis in the municipality of Bela Vista, state of Mato Grosso do Sul, Brazil, and the absence of information on its vectors in this area led the ...
ALVES, Murilo Andrade, ALVES, Tulia Peixoto, BRAZIL, Reginaldo Peçanha, CRISTALDO, Geucira, CUNHA, Rivaldo Venâncio da, DORVAL, Maria Elizabeth C, GALATI, Eunice Aparecida Bianchi, OLIVEIRA, Alessandra Gutierrez de, OSHIRO, Elisa Teruya, ROCHA, Hilda Carlos da   +9 more
core   +3 more sources

The Role of Cytoplasmic mRNA Cap-Binding Protein Complexes in Trypanosoma brucei and Other Trypanosomatids. [PDF]

, 2017
Trypanosomatid protozoa are unusual eukaryotes that are well known for having unusual ways of controlling their gene expression. The lack of a refined mode of transcriptional control in these organisms is compensated by several post-transcriptional ...
Campbell, David A, de Melo Neto, Osvaldo P, Freire, Eden R, Sturm, Nancy R   +3 more
core   +2 more sources

Differentiation of Leishmania (L.) infantum, Leishmania (L.) amazonensis and Leishmania (L.) mexicana Using Sequential qPCR Assays and High-Resolution Melt Analysis

Microorganisms, 2020
Leishmania protozoa are the etiological agents of visceral, cutaneous and mucocutaneous leishmaniasis. In specific geographical regions, such as Latin America, several Leishmania species are endemic and simultaneously present; therefore, a diagnostic method for species discrimination is warranted.
Marcello Ceccarelli, Aurora Diotallevi, Gloria Buffi, Mauro De Santi, Edith A. Fernández-Figueroa, Claudia Rangel-Escareño, Said A. Muñoz-Montero, Ingeborg Becker, Mauro Magnani, Luca Galluzzi   +9 more
openaire   +3 more sources

Iron metabolism in trypanosomatids, and its crucial role in infection. [PDF]

, 2010
Iron is almost ubiquitous in living organisms due to the utility of its redox chemistry. It is also dangerous as it can catalyse the formation of reactive free radicals - a classical double-edged sword.
Kelly, JM, Taylor, MC
core   +1 more source

Canine Leishmaniasis in Rio de Janeiro, Brazil (2000–2015): Taxonomic Characterisation of Etiological Agents and Geospatial Case Analysis

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Canine Leishmaniasis is a vector‐borne zoonotic disease caused by several species of protozoa of the genus Leishmania. In the state of Rio de Janeiro (RJ), Leishmania braziliensis is the most prevalent species causing tegumentary leishmaniasis (TL) and Leishmania infantum is the main causative agent of visceral leishmaniasis (VL).
Luciana de Freitas Campos Miranda, Laryssa Fabiano do Rosário Coelho, Samanta Cristina das Chagas Xavier, Artur Augusto Velho Mendes Junior, Renan Nunes Albuquerque, Aline Fagundes da Silva, Andreza Pain Marcelino, Fernanda Nunes Santos, Sandro Antonio Pereira, Rodrigo Caldas Menezes, Armando de Oliveira Schubach   +10 more
wiley   +1 more source

Antiprotozoal activity of flavonoids from Eupatorium arnottianum [PDF]

, 2017
Dichloromethane and ethanol extracts of Eupatorium arnottianum were evaluated for invitroleishmanicidal activity. The dichloromethane extract produced 80% and 85% of growthinhibition on both Leishmania mexicana and Leishmania amazonensis promastigotes ...
Cazorla, Silvia Ines, Clavin, Maria Liliana, Frank, Fernanda María, Malchiodi, Emilio Luis, Martino, Virginia Susana, Muschietti, Liliana Victoria, Sosa, Miguel Angel, Spina Zapata, Renata María   +7 more
core  

In silico predicted epitopes from the COOH-terminal extension of cysteine proteinase B inducing distinct immune responses during Leishmania (Leishmania) amazonensis experimental murine infection [PDF]

, 2011
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular e Doenças Endêmicas.
Bernardo AS Pereira, Franklin S Silva, Karina M Rebello, Marcel Marín-Villa, Yara M Traub-Cseko, Thereza CB Andrade, Álvaro L Bertho, Ernesto R Caffarena, Carlos R Alves   +8 more
core   +2 more sources

Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz, Ibrahim Tokmak, Muzaffer Yildirim, Tugce Canavar Yildirim, Elif Sena Ozkoc, Irem Evcili, Emre Mert Ipekoglu, İhsan Cihan Ayanoglu, Emre Dunuroglu, Dicle Caliskan, Harun Onler, Zeynep Arzum, Ceren Ulker, Olcay Mert, Ridvan Orkut, Ibrahim Oguzhan Tarman, Ulku Guler, Bekir Salih, Volkan Yazar, Gokcen Ozgun, Serap Birincioglu, Ahmet Ozbilgin, Bilgi Gungor, Ihsan Gursel, Mayda Gursel   +24 more
wiley   +1 more source

Metabolomic Profile of BALB/c Macrophages Infected with Leishmania amazonensis: Deciphering L-Arginine Metabolism [PDF]

International Journal of Molecular Sciences, 2019
Background: Leishmaniases are neglected tropical diseases that are caused by Leishmania, being endemic worldwide. L-arginine is an essential amino acid that is required for polyamines production on mammal cells. During Leishmania infection of macrophages, L-arginine is used by host and parasite arginase to produce polyamines, leading to parasite ...
Sandra Marcia Muxel, Maricruz Mamani-Huanca, Juliana Ide Aoki, Ricardo Andrade Zampieri, Lucile Maria Floeter-Winter, Ángeles López-Gonzálvez, Coral Barbas   +6 more
openaire   +2 more sources