Results 71 to 80 of about 72,689 (297)

Assessment of Serum Leptin Level and Insulin Resistance in Obese Subjects

Journal of Rawalpindi Medical College, 2012
Background: To determine the relationship between serum leptin and insulin resistance in obese Pakistani subjects. Methods: In this observational study fifty healthy obese and overweight subjects were selected by nonprobability convenience sampling. Age,
Ahsan Kazmi
doaj  

Altered leptin signaling and attenuated cardiac vagal activity in rats with type 2 diabetes

Frontiers in Physiology
IntroductionThe leading cause of death in type 2 diabetes mellitus (T2DM) patients is cardiovascular-related events, including myocardial infraction-induced ventricular arrhythmia.
Anthony J. Evans, Huiyin Tu, Yu Li, Boris Shabaltiy, Lauren Whitney, Kassidy Carpenter, Yu-long Li, Yu-long Li   +7 more
doaj   +1 more source

Leptin therapy, insulin sensitivity, and glucose homeostasis

Indian Journal of Endocrinology and Metabolism, 2012
Glucose homeostasis is closely regulated not only by insulin, but also by leptin. Both hormones act centrally, regulating food intake and adiposity in humans. Leptin has several effects on the glucose-insulin homeostasis, some of which are independent of
Gilberto Paz-Filho, Claudio Mastronardi, Ma-Li Wong, Julio Licinio   +3 more
doaj   +1 more source

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source

Insulin resistance, level of leptin and body mass index in patients with coronary artery disease combined with nonalcoholic liver steatosis [PDF]

, 2022
Mariya Grechanyk, O. V. Kuryata
openalex   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Correlation Analysis of Body Weight with Insulin Resistance and Leptin Levels in Farm Workers

Journal of Agromedicine and Medical Sciences (AMS)
Insulin resistance is a pathological condition resulting from impaired insulin response which causes increased insulin production as a form of compensation from pancreatic beta cells. A stable body weight can prevent insulin resistance and excessive body
Naurah Nazihah Azzalina, Sugiyanta Sugiyanta, Kristianningrum Dian Sofiana   +2 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Circumventing leptin resistance for weight control [PDF]

Proceedings of the National Academy of Sciences, 2001
In the avalanche of recent information on the brain's control of energy homeostasis and the pathophysiology of obesity, there are two outstanding insights. One is enhanced knowledge of the neuroanatomy and neurochemistry of various components of the appetite regulation and energy expenditure networks in the hypothalamus, and the other is ...
openaire   +2 more sources

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source