Results 51 to 60 of about 2,304,681 (286)
Association of 25 (OH) Vitamin D and leptin in individuals with insulin resistance
Indian Journal of Endocrinology and Metabolism, 2022 Introduction: Asian-Indian individuals with diabetes have been shown to have low vitamin D levels. Whether this hypovitamonisis D is associated with hyperleptinaemia is unclear.
S V Madhu +4 more
doaj +1 more source
Leptin Resistance and the Neuro-Adipose Connection [PDF]
Frontiers in Endocrinology, 2017 This article was submitted to Cellular Endocrinology, a section of the journal Frontiers in Endocrinology.
Barateiro, A, Mahú, I, Domingos, A
openaire +3 more sources
Differences in zinc status and the leptin axis in anorexic and recovered adolescents and young adults : a pilot study [PDF]
, 2012 Background: Evidence from animal studies suggests that leptin metabolism is associated with zinc (Zn) status. However, research investigating this relationship in adolescents and young adults with anorexia nervosa (AN) is scarce; the present study aims ...
Wöckel, Lars +31 more
core +1 more source
BMC Pediatrics, 2022 Background Obesity usually complicates hypothyroidism. Adipokines like leptin and adiponectin secreted by adipose tissue modulate insulin resistance (IR), appetite, and obesity.
Doaa El Amrousy +2 more
doaj +1 more source
Effect of obesity and serum leptin level on clopidogrel resistance
Türk Kardiyoloji Derneği Arşivi, 2016 Objective: Clopidogrel inhibits platelet aggregation by blockade of platelet adenosine diphosphate (ADP) P2Y12 receptor. Leptin is the obesity gene product, and its serum level increases with obesity.
Ali Dogan +5 more
doaj +1 more source
Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans [PDF]
, 2008 Includes abstract.Includes bibliographical references (leaves 226-256).Obesity is a worldwide problem and is a factor in the pathogenesis of the metabolic syndrome and kidney disease through the development of obesity-related hypertension and ...
Okpechi, Ikechi Gareth
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]
, 2014 Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Bloom, SR +5 more
core +1 more source
AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing
Advanced Science, EarlyView.A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li +8 more
wiley +1 more source
Physiological leptin resistance [PDF]
Medycyna Weterynaryjna, 2016 Leptin is an adipose tissue-derived hormone whose circulating levels correlate with the amount of body fat stores. The main function of this adipokine is to regulate energy metabolism. By modulating the expression of orexigenic and anorexigenic neuropeptides in the hypothalamus, leptin reduces appetite.
Patrycja Gogga +3 more
openaire +1 more source