Results 41 to 50 of about 21,470 (214)
Frontiers in Plant Science, 2014 Following the description of SAD1/UNC84 (SUN) domain proteins in higher plants, evidence has rapidly increased that plants contain a functional Linker of Nucleoskeleton and Cytoskeleton (LINC) complex bridging the nuclear envelope (NE).
David Edgar Evans +3 more
doaj +1 more source
The Role of the LINC Complex in Sperm Development and Function. [PDF]
Int J Mol Sci, 2020 The LINC (LInker of Nucleoskeleton and Cytoskeleton) complex is localized within the nuclear envelope and consists of SUN (Sad1/UNc84 homology domain-containing) proteins located in the inner nuclear membrane and KASH (Klarsicht/Anc1/Syne1 homology domain-containing) proteins located in the outer nuclear membrane, hence linking nuclear with cytoplasmic
Kmonickova V +3 more
europepmc +4 more sources
The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA [PDF]
, 2016 Alterations in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells.
Bozzoni, Irene +8 more
core +2 more sources
Molecular models of LINC complex assembly at the nuclear envelope [PDF]
Journal of Cell Science, 2021 ABSTRACT Large protein complexes assemble at the nuclear envelope to transmit mechanical signals between the cytoskeleton and nucleoskeleton. These protein complexes are known as the linkers of the nucleoskeleton and cytoskeleton complexes (LINC complexes) and are formed by the interaction of SUN and KASH domain proteins in the nuclear ...
Zeinab Jahed +4 more
openaire +2 more sources
Pushing the (nuclear) envelope into meiosis. [PDF]
, 2013 A recent study shows that a short isoform of a mammalian nuclear lamin is important for homologous chromosome interactions during meiotic prophase in ...
Dernburg, Abby F
core +1 more source
Cell Mechanosensitivity Is Enabled by the LINC Nuclear Complex [PDF]
Current Molecular Biology Reports, 2016 Mechanoresponses in mesenchymal stem cells (MSCs) guide both differentiation and function. In this review, we focus on advances in0 our understanding of how the cytoplasmic cytoskeleton, nuclear envelope and nucleoskeleton, which are connected via LINC (Linker of Nucleoskeleton and Cytoskeleton) complexes, are emerging as an integrated dynamic ...
Gunes, Uzer +2 more
openaire +2 more sources
The LINC Between Mechanical Forces and Chromatin
Frontiers in Physiology, 2021 The heart continually senses and responds to mechanical stimuli that balance cardiac structure and activity. Tensile forces, compressive forces, and shear stress are sensed by the different cardiac cell types and converted into signals instructing proper
Olga Lityagina +2 more
doaj +1 more source
Increasing the talk-time of mobile radios with efficient linear transmitter architectures [PDF]
, 2000 In order to meet the linearity specification of standards such as GSM EDGE and TETRA the power amplifier (PA) linearisation methods in common usage today result in low DC to RF efficiency (e.g. Cartesian loop and adaptive predistortion).
Beach, MA +3 more
core +2 more sources
Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization. [PDF]
PLoS Genetics, 2014 Proteins of the nuclear envelope (NE) are associated with a range of inherited disorders, most commonly involving muscular dystrophy and cardiomyopathy, as exemplified by Emery-Dreifuss muscular dystrophy (EDMD).
Peter Meinke +10 more
doaj +1 more source
LINC complex alterations in DMD and EDMD/CMT fibroblasts [PDF]
European Journal of Cell Biology, 2012 Emery-Dreifuss muscular dystrophy (EDMD) is a late onset-disease characterized by skeletal muscle wasting and heart defects with associated risk of sudden death. The autosomal dominant form of the disease is caused by mutations in the LMNA gene encoding LaminA and C, the X-linked form results from mutations in the gene encoding the inner nuclear ...
Taranum, Surayya +8 more
openaire +2 more sources