Results 51 to 60 of about 21,470 (214)
eLife, 2023 Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via regulation of cell-cell junctions.
Danielle B Buglak +16 more
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Birth of a Regulatory Long Non-coding RNA/Gene, linc-UR-UB
Frontiers in Genetics, 2021 The origin of genes has been a major topic of research for many years, albeit in some cases, it has been a difficult process to elucidate. Insightful is a recent publication that experimentally shows how one gene, linc-UR-UB was born.
Nicholas Delihas
doaj +1 more source
Complex Hyperbolic Structures on Disc Bundles over Surfaces [PDF]
, 2011 We study complex hyperbolic disc bundles over closed orientable surfaces that arise from discrete and faithful representations H_n->PU(2,1), where H_n is the fundamental group of the orbifold S^2(2,...,2) and thus contains a surface group as a subgroup ...
Anan'in, Sasha +2 more
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Chain reaction: LINC complexes and nuclear positioning [PDF]
F1000Research, 2019 Nuclear positioning plays an essential role in defining cell architecture and behaviour in both development and disease, and nuclear location frequently adjusts according to internal and external cues. For instance, during periods of migration in many cell types, the nucleus may be actively repositioned behind the microtubule-organising centre. Nuclear
openaire +2 more sources
Cells, 2020 Vascular smooth muscle cells (VSMCs) are the predominant cell type in the blood vessel wall. Changes in VSMC actomyosin activity and morphology are prevalent in cardiovascular disease. The actin cytoskeleton actively defines cellular shape and the LInker
Lauren Porter +12 more
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Nucleus, 2019 The linker of nucleoskeleton and cytoskeleton (LINC) complex is an essential multi-protein structure spanning the eukaryotic nuclear envelope. The LINC complex functions to maintain nuclear architecture, positioning, and mobility, along with specialized ...
Hardeep K. Gumber +6 more
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Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]
, 2019 Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico +13 more
core +1 more source
The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]
, 2020 [Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida +6 more
core +1 more source
Cell Mechanosensitivity to Extremely Low Magnitude Signals is Enabled by a LINCed Nucleus [PDF]
, 2015 A cell's ability to recognize and adapt to the physical environment is central to its survival and function, but how mechanical cues are perceived and transduced into intracellular signals remains unclear. In mesenchymal stem cells (MSCs), high-magnitude
Bas, Guniz +11 more
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Mechanical Characterization of Glandular Acini Using a Micro-indentation Instrument
Bio-Protocol, 2020 The linker of nucleoskeleton and cytoskeleton (LINC) complex is responsible for tethering the nucleus to the cytoskeleton, providing a pathway for the cell’s nucleus to sense mechanical signals from the environment.
Christopher O'Bryan +3 more
doaj +1 more source