Frontiers in Microbiology, 2021 Vancomycin-resistant Enterococcus faecium (VREF) and methicillin-resistant Staphylococcus aureus (MRSA) are associated with significant health burden. We investigated linezolid and daptomycin resistance among VREF and MRSA in the EU/EEA between 2014 and ...
Robby Markwart +4 more
doaj +1 more source
International Journal of Medical Microbiology, 2021 We aim to describe the epidemiological, clinical and microbiological characteristics of the linezolid- and vancomycin- resistant Enterococcus faecium (LVRE) in a tertiary care hospital in Germany.We conducted a retrospective analysis of 196 LVRE cases observed from 1st January 2012 to 31th December 2018.
Flaminia Olearo +9 more
openaire +3 more sources
Circulation of Highly Drug-Resistant Clostridium difficile Ribotypes 027 and 001 in Two Tertiary-Care Hospitals in Mexico [PDF]
, 2018 © 2018, Mary Ann Liebert, Inc.OBJECTIVE: To assess drug susceptibility and characterize Clostridium difficile ribotypes in isolates from two tertiary-care hospitals in Mexico.
Adrian Martinez-Melendez, Adrian +10 more
core +2 more sources
Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid. [PDF]
, 2007 Linezolid, which targets the ribosome, is a new synthetic antibiotic that is used for treatment of infections caused by Gram-positive pathogens. Clinical resistance to linezolid, so far, has been developing only slowly and has involved exclusively target
Arias, Cesar A +6 more
core +1 more source
Frontiers in Microbiology, 2021 Enterococci, the main pathogens associated with nosocomial infections, are resistant to many common antibacterial drugs including β-lactams, aminoglycosides, etc.
Lifang Jiang +13 more
doaj +1 more source
Impact of time to appropriate therapy on mortality in patients with vancomycin-intermediate Staphylococcus aureus infection [PDF]
, 2016 Despite the increasing incidence of vancomycin-intermediate Staphylococcus aureus (VISA) infections, few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in VISA patients.
Burnham, Carey-Ann D +3 more
core +2 more sources
Prevalence of Mycobacterium tuberculosis resistant to bedaquiline and delamanid in China
Journal of Global Antimicrobial Resistance, 2021 : Objectives: The new antituberculous drugs delamanid and bedaquiline form the last line of defence against drug-resistant tuberculosis (TB). Understanding the background prevalence of resistance to new drugs can help predict the lifetime of these drugs’
Wencong He +11 more
doaj +1 more source
Analysis of two pheromone-responsive conjugative multiresistance plasmids carrying the novel mobile optrA locus from Enterococcus faecalis [PDF]
, 2019 Background: The acquired optrA gene, which encodes a ribosomal protection protein of the ABC-F family, can confer cross-resistance to linezolid and florfenicol, posing a serious therapeutic challenge to both human and veterinary medicine.
Chen, Yu-Xia +7 more
core +1 more source
High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]
, 2019 Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon +9 more
core +2 more sources
Linezolid-ResistantStaphylococcus cohnii,Greece
Emerging Infectious Diseases, 2009 To the Editor: Since 2003, linezolid has typically been used to treat infections caused by multidrug-resistant gram-positive cocci such as vancomycin-resistant Enterococcus faecium and methicillin-resistant Staphylococcus aureus (1). In Greece, a major problem is nosocomial dissemination of vancomycin-resistant enterococci.
Efi Petinaki +8 more
openaire +3 more sources