Results 21 to 30 of about 41,061 (224)

Evaluation of Sensitivity and Resistance of Linezolid in Pre Extensively Drug Resistance Tuberculosis and Extensively Drug Resistance Tuberculosis at a Tertiary Care Hospital, Jamnagar, Gujarat, India [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: The diseases have a high prevalence in India, accounting for one fourth of the Tuberculosis (TB) cases in the world. The situation becomes more complicated due to the rising of Human Immunodeficiency virus/AIDS pandemic, the emergence of ...
Dipali Maganbhai Gavali, Binita Aring, Summiya Mullan, Akhlakahemad A Nathametha, Abhishek B Dave   +4 more
doaj   +1 more source

The emergence of plasmid-borne cfr-mediated linezolid resistant-staphylococci in Vietnam

Journal of Global Antimicrobial Resistance, 2020
Objectives: Linezolid is one of the last resort antibiotics effectively used in the treatment of infections caused by multidrug-resistant Gram-positive bacteria.
Le Thuy Thi Nguyen, Khanh Ngau Thi Nguyen, Phuc Nhi Thi Anh Le, Fabio Cafini, Ben Pascoe, Samuel K. Sheppard, Thanh Bao Nguyen, Thien Phuc Hoang Nguyen, Thuy Vy Nguyen, Tram T.K. Pham, Kazuya Morikawa, Dang Quan Nguyen, Hoa Xo Duong   +12 more
doaj   +1 more source

Linezolid-Resistant Enterococcus spp. Isolates from Foods of Animal Origin—The Genetic Basis of Acquired Resistance

Foods, 2022
Enterococci are important opportunistic pathogens with the capacity to acquire and spread antibiotic resistance. At present, linezolid-resistant enterococci (LRE) pose a great challenge.
Urszula Zarzecka, Arkadiusz Józef Zakrzewski, Wioleta Chajęcka-Wierzchowska, Anna Zadernowska   +3 more
doaj   +1 more source

Linezolid Resistance against Gram Positive Bacteria Isolated from Blood Stream Infections: A Challenging Threat

Journal of Pure and Applied Microbiology, 2022
The gradual rise of multidrug resistant micro-organisms is a national concern for all health care providers. Linezolid belongs to the oxazolidinone class of antimicrobials.
Satish Chandel, Anuradha Dubey, Parag Sharma, Ramesh Agrawal   +3 more
doaj   +1 more source

Linezolid for drug-resistant pulmonary tuberculosis [PDF]

Cochrane Database of Systematic Reviews, 2019
Linezolid was recently re-classified as a Group A drug by the World Health Organization (WHO) for treatment of multi-drug resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB), suggesting that it should be included in the regimen for all patients unless contraindicated.
Singh, Bhagteshwar, Cocker, Derek, Ryan, Hannah, Sloan, Derek J   +3 more
openaire   +4 more sources

Linezolid-resistant enterococci in Polish hospitals: species, clonality and determinants of linezolid resistance [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2017
The significant increase of the linezolid-resistant enterococci (LRE) has been observed in Polish hospitals since 2012 and our study aimed at elucidating the possible reasons for this phenomenon. Polish LRE isolates were analysed by multilocus-sequence typing (MLST) and multiple locus variable-number tandem repeat (VNTR) analysis (MLVA), polymerase ...
Gawryszewska, I., Żabicka, D., Hryniewicz, W., Sadowy, E.   +3 more
openaire   +2 more sources

Resistance to Linezolid [PDF]

, 2017
Linezolid is an antimicrobial agent that binds to the bacterial ribosome and thereby inhibits protein synthesis. Soon after its release as a clinical drug, it became clear that bacteria could become resistant to linezolid. The resistance mechanisms are mainly causing alteration of the drug target site, but probably efflux might also play a role.
Vester, Birte, Ntokou, Eleni
openaire   +1 more source

Phenotypic and genotypic characterisation of linezolid-resistant coagulase-negative staphylococci possessing cfr-carrying plasmid

Journal of Global Antimicrobial Resistance, 2022
: Objectives: Linezolid-dependent growth has contributed to wide dissemination of Staphylococcus epidermidis in hospitals. This study aimed to characterise linezolid-resistant coagulase-negative staphylococci (CoNS) isolates and the possibility of ...
Fei Jiang, Ziyan Kong, Ke Liu, Chen Cheng, Tingting Jiang, Ping Ma, Rongpeng Li   +6 more
doaj   +1 more source

Detection of linezolid resistance cfr gene among MRSA isolates

Journal of Infection and Public Health, 2022
Background: Linezolid (Oxazolidinones) is commonly used against a variety of Gram-positive infections, especially methicillin-resistant Staphylococcus aureus (MRSA).
Muneeba Wali, Mir Sadiq Shah, Tayyab Ur Rehman, Hammad Wali, Masroor Hussain, Laiq Zaman, Fahim Ullah Khan, Autif Hussain Mangi   +7 more
doaj   +1 more source

Linezolid-Resistant, Vancomycin-Resistant Enterococcus faecium Infection in Patients without Prior Exposure to Linezolid [PDF]

Clinical Infectious Diseases, 2003
We describe 2 patients without prior exposure to linezolid who were infected with closely related strains of linezolid- and vancomycin-resistant Enterococcus faecium (LRVREF) that may have been hospital acquired. Polymerase chain reaction amplification of the domain V region of the 23S ribosomal RNA gene demonstrated the presence of the G2576U mutation
Sibtain, Rahim, Satish K, Pillai, Howard S, Gold, Lata, Venkataraman, Kenneth, Inglima, Robert A, Press   +5 more
openaire   +2 more sources