Results 201 to 210 of about 122,182 (249)

Novel lipid nanoparticle in a mRNA cancer vaccine drives tumor control via type I IFNs and effector CD8<sup>+</sup> T cells. [PDF]

open access: yesMol Ther Nucleic Acids
Gold MJ   +14 more
europepmc   +1 more source
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CD1 and lipid antigens: intracellular pathways for antigen presentation

Current Opinion in Immunology, 2001
Recently, different members of the CD1 family of MHC-like molecules have been shown to sample different intracellular compartments to present lipid and glycolipid antigens to T cells. Emerging models suggest that CD1 may have evolved to monitor the integrity of membrane lipids and/or to present microbial lipid antigens to both alpha beta and gamma ...
Albert Bendelac   +1 more
exaly   +3 more sources

T cells specific for lipid antigens

Immunologic Research, 2012
Lipid-specific T cells are important participants in human immune responses. Recognition of lipid antigens contributes to host defense against pathogens that can cause debilitating diseases, including mycobacterial, viral, and parasitic infections. Lipid-specific T cells also play important roles in various autoimmune diseases, atherosclerosis, and in ...
Lucia Mori, Gennaro De Libero
exaly   +4 more sources

Lipid A and liposomes containing lipid A as antigens and adjuvants

Vaccine, 2008
Lipid A derived from Gram-negative bacterial lipopolysaccharide is a potent adjuvant and antigen. Incorporation of lipid A into liposomes renders the liposomes themselves immunogenic, resulting in generation of specific antibodies that recognize either the individual liposomal lipids, or the unique pattern presented by the combination of lipids.
Carl R, Alving, Mangala, Rao
openaire   +2 more sources

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