Results 221 to 230 of about 122,182 (249)
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How the immune system detects lipid antigens
Progress in Lipid Research, 2010T lymphocytes are the cells of the immune system that may recognize glycolipids as antigens. T cells recognize lipids associated with the non-polymorphic molecules of the CD1 family present on the membrane of antigen-presenting cells. CD1 molecules contain hydrophobic pockets, which bind a large variety of lipid molecules in various manners.
De Libero, Gennaro, Mori, Lucia
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Cationic supported lipid bilayers for antigen presentation
International Journal of Pharmaceutics, 2007Polystyrene sulfate (PSS) particles (301 nm mean diameter) were covered with single cationic dioctadecyldimethylammonium bromide (DDA) bilayers and used for antigen adsorption and presentation. The antigen was a mixture of purified 18/14 Taenia crassiceps proteins (18/14-Tcra).
N, Lincopan +3 more
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Apolipoprotein-mediated pathways of lipid antigen presentation
Nature, 2005Peptide antigens are presented to T cells by major histocompatibility complex (MHC) molecules, with endogenous peptides presented by MHC class I and exogenous peptides presented by MHC class II. In contrast to the MHC system, CD1 molecules bind lipid antigens that are presented at the antigen-presenting cell (APC) surface to lipid antigen-reactive T ...
Peter, van den Elzen +13 more
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The cellular and biochemical rules of lipid antigen presentation
European Journal of Immunology, 2009AbstractThe recognition of both protein and lipid antigens follows similar strategies that rely on different molecular mechanisms. APC present lipid antigens exploiting the same mechanisms implicated in lipid translocation, lipoprotein assembly and lipid degradation. An important issue is how the lipid structure contributes to antigenicity.
De Libero, Gennaro +2 more
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Lipid based particulate formulations for the delivery of antigen
Immunology & Cell Biology, 2005Particulate adjuvant systems are largely classified according to their functional characteristics, such as the nature of the typical immune response they induce, or their perceived mode of action. From a formulation science perspective, it is practical to classify antigen delivery systems according to the physical nature of the formulations.
Copland, Melissa J. +3 more
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Antigenicity of Lipid-Adsorbed Diphtheria and Tetanus Toxoids
The Journal of Immunology, 1964Summary Studies of the effectiveness of hexadecylamine (HDA)-adsorbed vaccines have been extended to bacterial as well as viral antigens. Adsorption experiments show that diphtheria and tetanus toxoids adsorb to HDA with great efficiency whereas about 30 to 40% of the protein, which is not toxoid, does not adsorb.
J S, YOUNGNER, V, AXELROD
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Lipid-Protamine-DNA-Mediated Antigen Delivery
Current Drug Delivery, 2005The development of novel 'new generation' vaccine systems that is based on proteins, peptides or DNA is of great current interest. However, due to the lower efficiencies of these new generation vaccines, they are seldomly used alone. Rather, their formulations often contain adjuvants, either to enhance the immune responses or to reduce dosing.
Dileep Padinjarae, Vangasseri +2 more
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Critical care management of chimeric antigen receptor T-cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Sandrine Valadè +2 more
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