Results 161 to 170 of about 273,083 (353)

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

Mechanism of ochratoxin a-stimulated lipid peroxidation

, 1990
Ochratoxin A (OTA) is a mycotoxin and a nephrotoxic carcinogen. The mechanism by which it stimulates lipid peroxidation was investigated in a reconstituted system consisting of phospholipid vesicles (liposomes), flavoprotein NADPH-cytochrome P-450 ...
Omar, Rabeea Fahmy
core  

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

NSDHL as a regulator of lipid peroxidation and ER stress-mediated apoptosis in ovarian cancer. [PDF]

Biol Direct
Shanshan X, Jinshi R, Wanlin C, Yuwan L, Hanye J, Shizhou Y, Weidong F, Huimei Z, Yongmei X, Weiguo L.   +9 more
europepmc   +1 more source

Protective Effect of Carvedilol on Paracetamol-induced Hepatotoxicity; Role of Modulation Inflammation and Lipid Peroxidation [PDF]

, 2016
Heba M. Mahmoud, Amira M. Abo‐Youssef, Ali A. Abo‐Saif   +2 more
openalex   +1 more source

lipid peroxide, peroxidized lipid

NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI, 1995
openaire   +2 more sources

Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays

Advanced Science, EarlyView.
An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen, Bin Li, Yingying Wang, Fulin Zhu, Wenxuan Yang, Xuanyu Fu, Tiantian Man, Qiuyue Wu, Kewei Ren, Shengyuan Deng   +9 more
wiley   +1 more source

ADH4 deficiency activates the NRF2-CSF1 axis by increased lipid peroxidation in hepatocellular carcinoma. [PDF]

Cancer Cell Int
Yan P, Luo Y, Peng D, Mou T, Lei D, Li S, Yu H, Huang Z, Wu Z.   +8 more
europepmc   +1 more source

Lipid peroxidation levels in soybean (Glycine max (L.) Merr.) seed parts as a consequence on imbibition stress

, 2009
High rainfall and rapid water uptake by dry seed after sowing in the field can result in so-called seed imbibitional damage. Here, lipid peroxidation levels were evaluated in seed testa, embryos and cotyledons of three soybean cultivars (Podravka 95 ...
Wilson, Ian D., Civale, Leon, Teklic, T, Hancock, John T., Lisjak, M   +4 more
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