Drought and heat stress mediated activation of lipid signaling in plants: a critical review [PDF]
Frontiers in Plant Science, 2023 Lipids are a principal component of plasma membrane, acting as a protective barrier between the cell and its surroundings. Abiotic stresses such as drought and temperature induce various lipid-dependent signaling responses, and the membrane lipids ...
Parul Sharma +7 more
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Lipid Signaling During Gamete Maturation. [PDF]
Front Cell Dev Biol, 2022 Cell lipids are differentially distributed in distinct organelles and within the leaflets of the bilayer. They can further form laterally defined sub-domains within membranes with important signaling functions.
Mostafa S, Nader N, Machaca K.
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Lipid Signaling in Ocular Neovascularization. [PDF]
Int J Mol Sci, 2020 Vasculogenesis and angiogenesis play a crucial role in embryonic development. Pathological neovascularization in ocular tissues can lead to vision-threatening vascular diseases, including proliferative diabetic retinopathy, retinal vein occlusion ...
Terao R, Kaneko H.
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Mitochondrial Lipid Signaling and Adaptive Thermogenesis. [PDF]
Metabolites, 2021 Thermogenesis is an energy demanding process by which endotherms produce heat to maintain their body temperature in response to cold exposure. Mitochondria in the brown and beige adipocytes play a key role in thermogenesis, as the site for uncoupling ...
Von Bank H +3 more
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Fight Hard or Die Trying: Current Status of Lipid Signaling during Plant-Pathogen Interaction. [PDF]
Plants (Basel), 2021 Plant diseases pose a substantial threat to food availability, accessibility, and security as they account for economic losses of nearly $300 billion on a global scale.
Mehta S +4 more
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Parasitic nematode fatty acid- and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways. [PDF]
PLoS Pathog, 2021 Parasitic nematodes cause significant morbidity and mortality globally. Excretory/secretory products (ESPs) such as fatty acid- and retinol- binding proteins (FARs) are hypothesized to suppress host immunity during infection, yet little is known about ...
Parks SC +13 more
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Bioactive lipid signaling and lipidomics in macrophage polarization: Impact on inflammation and immune regulation. [PDF]
Front ImmunolMacrophages, crucial innate immune cells, defend against pathogens and resolve inflammation, maintaining tissue balance. They perform phagocytosis, present antigens to T cells, and bond innate and adaptive immunity through various activation states ...
RodrÃguez JP +3 more
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Bioactive Lipid Signaling in Cardiovascular Disease, Development, and Regeneration. [PDF]
Cells, 2020 Cardiovascular disease (CVD) remains a leading cause of death globally. Understanding and characterizing the biochemical context of the cardiovascular system in health and disease is a necessary preliminary step for developing novel therapeutic ...
Wasserman AH, Venkatesan M, Aguirre A.
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J Cell Sci, 2021 Sortilin is a receptor for neuronal uptake of apolipoprotein E. Sortilin-dependent uptake of lipidated apoE promotes conversion of polyunsaturated fatty acids (PUFA) into neuromodulators that induce anti-inflammatory gene expression in the brain.
Asaro A +11 more
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Sphingosine 1-phosphate: Lipid signaling in pathology and therapy. [PDF]
Science, 2019 Mediating systemic health Sphingosine 1-phosphate (S1P) is an important circulating lipid mediator that is derived from the metabolism of cell membranes.
Cartier A, Hla T.
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