Lipid signaling in plants [PDF]
Membrane lipids provide both the structural basis for cell membranes and a rich source of cellular mediators that regulate many aspects of plant development and environmental interactions.
Xuemin Wang, K. Chapman
semanticscholar +5 more sources
FABP5 coordinates lipid signaling that promotes prostate cancer metastasis. [PDF]
Prostate cancer (PCa) is defined by dysregulated lipid signaling and is characterized by upregulation of lipid metabolism-related genes including fatty acid binding protein 5 (FABP5), fatty acid synthase (FASN), and monoacylglycerol lipase (MAGL).
Carbonetti G+6 more
europepmc +2 more sources
Pseudomonas aeruginosa Lipoxygenase LoxA Contributes to Lung Infection by Altering the Host Immune Lipid Signaling. [PDF]
Pseudomonas aeruginosa is an opportunistic bacteria and a major cause of nosocomial pneumonia. P. aeruginosa has many virulence factors contributing to its ability to colonize the host. LoxA is a lipoxygenase enzyme secreted by P.
Morello E+12 more
europepmc +2 more sources
Ferroptosis at the intersection of lipid metabolism and cellular signaling
Deguang Liang, Xuejun Jiang
exaly +2 more sources
Functions and Interaction of Plant Lipid Signaling under Abiotic Stresses.
Lipids are the primary form of energy storage and a major component of plasma membranes, which form the interface between the cell and the extracellular environment.
Yu Liang+4 more
semanticscholar +1 more source
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function
Cells respond to fluctuating nutrient supply by adaptive changes in organelle dynamics and in metabolism. How such changes are orchestrated on a cell-wide scale is unknown. We show that endosomal signaling lipid turnover by MTM1, a phosphatidylinositol 3-
Wonyul Jang+10 more
semanticscholar +1 more source
Raman microscopy-based quantification of the physical properties of intracellular lipids
Uematsu and Shimizu use Raman spectroscopy to quantify changes in the physical properties of lipid droplets (LDs) and in non-LD cell regions associated with alterations in saturated and unsaturated fatty acid availability in culture medium. Their results
Masaaki Uematsu, Takao Shimizu
doaj +1 more source
Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle
In Duchenne muscular dystrophy (DMD), lack of dystrophin increases the permeability of myofiber plasma membranes to ions and larger macromolecules, disrupting calcium signaling and leading to progressive muscle wasting. Although the biological origin and
William J. Valentine+15 more
doaj +1 more source
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe adverse effect observed in most patients treated with neurotoxic anti-cancer drugs. Currently, there are no therapeutic options available for the prevention of CIPN. Furthermore, few drugs are
Shota Yamamoto, Nobuaki Egashira
doaj +1 more source
Profiling of fatty acid metabolism in the dorsal root ganglion after peripheral nerve injury
Peripheral nerve injury (PNI) induces neuronal hyperexcitability, which underlies neuropathic pain. The emergence of RNA sequencing technologies has enabled profiling of transcriptional changes in pathological conditions. However, these approaches do not
Shota Yamamoto+5 more
doaj +1 more source