Results 11 to 20 of about 6,252,566 (347)
FABP5 coordinates lipid signaling that promotes prostate cancer metastasis. [PDF]
Sci Rep, 2019 Prostate cancer (PCa) is defined by dysregulated lipid signaling and is characterized by upregulation of lipid metabolism-related genes including fatty acid binding protein 5 (FABP5), fatty acid synthase (FASN), and monoacylglycerol lipase (MAGL).
Carbonetti G +6 more
europepmc +2 more sources
Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling. [PDF]
Biomolecules, 2023 Yu J +6 more
europepmc +3 more sources
Differential lipid signaling from CD4+ and CD8+ T cells contributes to type 1 diabetes development [PDF]
Frontiers in ImmunologyIntroductionWe reported that Ca2+-independent phospholipase A2β (iPLA2β)–derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. As CD4+ and CD8+ T cells are critical in promoting β-cell death, we tested the hypothesis that iDL signaling from ...
Tayleur D. White +24 more
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Synaptic lipid signaling [PDF]
Journal of Lipid Research, 2003 Neuronal cellular and intracellular membranes are rich in specialized phospholipids that are reservoirs of lipid messengers released by specific phospholipases and stimulated by neurotransmitters, neurotrophic factors, cytokines, membrane depolarization,
Nicolas G. Bazan
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Nuclear lipid signalling Symposium
European Journal of Histochemistry, 2009 Since 46 years ago, when Hokin and Hokin presented the first evidence of an enhanced incorporation of [32P] orthophosphate only into phosphatidylinositol (PI) after stimulation of tissue slices with acetylcholine, the biological role of phospholipids has been confined to the structural organisation of cellular membranes. Stemming from this pionieristic
F.A. Manzoli
openalex +4 more sources
Functions and Interaction of Plant Lipid Signaling under Abiotic Stresses.
Plant biology, 2023 Lipids are the primary form of energy storage and a major component of plasma membranes, which form the interface between the cell and the extracellular environment.
Yu Liang +4 more
semanticscholar +1 more source
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function
Science, 2022 Cells respond to fluctuating nutrient supply by adaptive changes in organelle dynamics and in metabolism. How such changes are orchestrated on a cell-wide scale is unknown. We show that endosomal signaling lipid turnover by MTM1, a phosphatidylinositol 3-
Wonyul Jang +10 more
semanticscholar +1 more source
Raman microscopy-based quantification of the physical properties of intracellular lipids
Communications Biology, 2021 Uematsu and Shimizu use Raman spectroscopy to quantify changes in the physical properties of lipid droplets (LDs) and in non-LD cell regions associated with alterations in saturated and unsaturated fatty acid availability in culture medium. Their results
Masaaki Uematsu, Takao Shimizu
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Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle
Frontiers in Physiology, 2022 In Duchenne muscular dystrophy (DMD), lack of dystrophin increases the permeability of myofiber plasma membranes to ions and larger macromolecules, disrupting calcium signaling and leading to progressive muscle wasting. Although the biological origin and
William J. Valentine +15 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Chemotherapy-induced peripheral neuropathy (CIPN) is a severe adverse effect observed in most patients treated with neurotoxic anti-cancer drugs. Currently, there are no therapeutic options available for the prevention of CIPN. Furthermore, few drugs are
Shota Yamamoto, Nobuaki Egashira
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