Results 21 to 30 of about 6,052,075 (348)

Hypoxia and lipid signaling [PDF]

Biological Chemistry, 2006
AbstractSufficient oxygen supply is crucial for the development and physiology of mammalian cells and tissues. When simple diffusion of oxygen becomes inadequate to provide the necessary flow of substrate, evolution has provided cells with tools to detect and respond to hypoxia by upregulating the expression of specific genes, which allows an ...
Huwiler, Andrea, Pfeilschifter, Josef
openaire   +5 more sources

Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids

iScience, 2020
Summary: Polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and arachidonic acid (ARA), play fundamental roles in mammalian physiology.
Daisuke Hishikawa, Keisuke Yanagida, Katsuyuki Nagata, Ayumi Kanatani, Yoshiko Iizuka, Fumie Hamano, Megumi Yasuda, Tadashi Okamura, Hideo Shindou, Takao Shimizu   +9 more
doaj   +1 more source

Maternal Transmission of Human OGG1 Protects Mice Against Genetically- and Diet-Induced Obesity Through Increased Tissue Mitochondrial Content

Frontiers in Cell and Developmental Biology, 2021
Obesity and related metabolic disorders are pressing public health concerns, raising the risk for a multitude of chronic diseases. Obesity is multi-factorial disease, with both diet and lifestyle, as well as genetic and developmental factors leading to ...
Natalie Burchat, Priyanka Sharma, Hong Ye, Sai Santosh Babu Komakula, Sai Santosh Babu Komakula, Agnieszka Dobrzyn, Agnieszka Dobrzyn, Vladimir Vartanian, R. Stephen Lloyd, R. Stephen Lloyd, Harini Sampath, Harini Sampath, Harini Sampath   +12 more
doaj   +1 more source

Quantification of Fatty Acids in Mammalian Tissues by Gas Chromatography–Hydrogen Flame Ionization Detection

Bio-Protocol, 2020
In mammalian organisms, fatty acids (FAs) exist mostly in esterified forms, as building blocks of phospholipids, triglycerides, and cholesteryl esters, while some exist as non-esterified free FAs. The absolute quantification of FA species in total lipids
Fumie Hamano, Suzumi Tokuoka, Tomomi Hashidate-Yoshida, Hideo Shindou, Takao Shimizu, Yoshihiro Kita   +5 more
doaj   +1 more source

Lipid signalling in pathogenic fungi [PDF]

Cellular Microbiology, 2010
In recent years, the study of lipid signalling networks has significantly increased. Although best studied in mammalian cells, lipid signalling is now appreciated also in microbial cells, particularly in yeasts and moulds. For instance, microbial sphingolipids and their metabolizing enzymes play a key role in the regulation of fungal pathogenicity ...
Arpita Singh, Maurizio Del Poeta
openaire   +3 more sources

Roles of Palmitoleic Acid and Its Positional Isomers, Hypogeic and Sapienic Acids, in Inflammation, Metabolic Diseases and Cancer

Cells, 2022
In the last few years, the monounsaturated hexadecenoic fatty acids are being increasingly considered as biomarkers of health with key functions in physiology and pathophysiology.
Miguel A. Bermúdez, Laura Pereira, Cristina Fraile, Laura Valerio, María A. Balboa, Jesús Balsinde   +5 more
doaj   +1 more source

Plasma Lipolysis and Changes in Plasma and Cerebrospinal Fluid Signaling Lipids Reveal Abnormal Lipid Metabolism in Chronic Migraine

Frontiers in Molecular Neuroscience, 2021
BackgroundLipids are a primary storage form of energy and the source of inflammatory and pain signaling molecules, yet knowledge of their importance in chronic migraine (CM) pathology is incomplete.
Katherine Castor, Jessica Dawlaty, Xianghong Arakaki, Xianghong Arakaki, Noah Gross, Yohannes W. Woldeamanuel, Michael G. Harrington, Michael G. Harrington, Michael G. Harrington, Robert P. Cowan, Alfred N. Fonteh, Alfred N. Fonteh   +11 more
doaj   +1 more source

Membrane lipids and cell signaling [PDF]

Current Opinion in Lipidology, 2017
Purpose of review Reception and transmission of signals across the plasma membrane has been a function generally attributed to transmembrane proteins. In the last 3 years, however, a growing number of reports have further acknowledged important contributions played by membrane lipids in the process of signal transduction.
Sunshine, Hannah, Iruela-Arispe, Maria Luisa   +1 more
openaire   +5 more sources

Diversity and function of membrane glycerophospholipids generated by the remodeling pathway in mammalian cells

Journal of Lipid Research, 2014
Cellular membranes are composed of numerous kinds of glycerophospholipids with different combinations of polar heads at the sn-3 position and acyl moieties at the sn-1 and sn-2 positions, respectively.
Daisuke Hishikawa, Tomomi Hashidate, Takao Shimizu, Hideo Shindou   +3 more
doaj   +1 more source

Chitosan Induces Plant Hormones and Defenses in Tomato Root Exudates

Frontiers in Plant Science, 2020
In this work, we use electrophysiological and metabolomic tools to determine the role of chitosan as plant defense elicitor in soil for preventing or manage root pests and diseases sustainably.
Marta Suarez-Fernandez, Marta Suarez-Fernandez, Frutos Carlos Marhuenda-Egea, Federico Lopez-Moya, Marino B. Arnao, Francisca Cabrera-Escribano, Maria Jose Nueda, Benet Gunsé, Luis Vicente Lopez-Llorca, Luis Vicente Lopez-Llorca   +9 more
doaj   +1 more source