Results 21 to 30 of about 75,579 (341)

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

open access: yesNature, 2020
Consumption of fructose has risen markedly in recent decades owing to the use of sucrose and high-fructose corn syrup in beverages and processed foods1, and this has contributed to increasing rates of obesity and non-alcoholic fatty liver disease2–4 ...
Steven Zhao   +16 more
semanticscholar   +1 more source

M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

open access: yesJournal of Hematology & Oncology, 2020
BackgroundLong non-coding RNAs (lncRNAs) possess significant regulatory functions in multiple biological and pathological processes, especially in cancer.
X. Zuo   +9 more
semanticscholar   +1 more source

Organismal Fructose Metabolism in Health and Non-Alcoholic Fatty Liver Disease

open access: yesBiology, 2020
NAFLD has alarmingly increased, yet FDA-approved drugs are still lacking. An excessive intake of fructose, especially in liquid form, is a dietary risk factor of NAFLD. While fructose metabolism has been studied for decades, it is still controversial how
Shea Skenderian   +2 more
doaj   +1 more source

Black Pepper or Radish Seed Oils in a New Combination of Essential Oils Modulated Broiler Chickens’ Performance and Expression of Digestive Enzymes, Lipogenesis, Immunity, and Autophagy-Related Genes

open access: yesVeterinary Sciences, 2022
Optimal combinations of essential oils (EOs) can enhance performance and maintain poultry productivity. The effects of EOs with black pepper oil (BPO) or radish seed oil (RSO) on performance and the expression of digestive enzymes, lipogenesis, immunity,
Asmaa T. Y. Kishawy   +7 more
doaj   +1 more source

Role of Protein Kinase CK2 in Aberrant Lipid Metabolism in Cancer

open access: yesPharmaceuticals, 2020
Uncontrolled proliferation is a feature defining cancer and it is linked to the ability of cancer cells to effectively adapt their metabolic needs in response to a harsh tumor environment.
Barbara Guerra, Olaf-Georg Issinger
doaj   +1 more source

Expression of STING in Women with Morbid Obesity and Nonalcoholic Fatty Liver Disease

open access: yesMetabolites, 2023
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic hepatic disease. Although mostly benign, this disease can evolve into nonalcoholic steatohepatitis (NASH).
Laia Bertran   +11 more
doaj   +1 more source

Fructose stimulated de novo lipogenesis is promoted by inflammation

open access: yesNature Metabolism, 2020
Benign hepatosteatosis, affected by lipid uptake, de novo lipogenesis and fatty acid (FA) oxidation, progresses to non-alcoholic steatohepatitis (NASH) on stress and inflammation.
Jelena Todoric   +25 more
semanticscholar   +1 more source

Changes in the sensitivity of lipogenesis in rat hepatocytes to hormones and precursors over the diurnal cycle and during longer-term starvation of donor animals.

open access: yesJournal of Lipid Research, 1984
In rat hepatocytes freshly isolated from donor rats at different times of the day, the rates of lipogenesis (de novo fatty acid synthesis) varied with a diurnal periodicity.
G F Gibbons   +2 more
doaj   +1 more source

PFOS-elicited metabolic perturbation in liver and fatty acid metabolites in testis of adult mice

open access: yesFrontiers in Endocrinology, 2023
IntroductionMultiple factors can contribute to sub-fecundity, including genetics, lifestyle, and environmental contaminants. PFASs are characterized as “forever chemicals” due to their ubiquitous contamination and their persistence in the environment ...
Wang Ka Lee   +7 more
doaj   +1 more source

Molecular Regulation of Lipogenesis, Adipogenesis and Fat Deposition in Chicken

open access: yesGenes, 2021
In the poultry industry, excessive fat deposition is considered an undesirable factor, affecting feed efficiency, meat production cost, meat quality, and consumer’s health.
Sara Nematbakhsh   +5 more
semanticscholar   +1 more source

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