Results 21 to 30 of about 51,491 (100)

AMPK β1 reduces tumor progression and improves survival in p53 null mice

Molecular Oncology, 2017
The AMP‐activated protein kinase (AMPK) is a heterotrimeric protein complex that is an important sensor of cellular energy status. Reduced expression of the AMPK β1 isoform has been linked to reduced survival in different cancers, but whether this ...
Vanessa P. Houde, Sara Donzelli, Andrea Sacconi, Sandra Galic, Joanne A. Hammill, Jonathan L. Bramson, Robert A. Foster, Theodoros Tsakiridis, Bruce E. Kemp, Giuseppe Grasso, Giovanni Blandino, Paola Muti, Gregory R. Steinberg   +12 more
doaj   +1 more source

Resveratrol: Anti-Obesity Mechanisms of Action

Molecules, 2014
Resveratrol is a non-flavonoid polyphenol which belongs to the stilbenes group and is produced naturally in several plants in response to injury or fungal attack. Resveratrol has been recently reported as preventing obesity.
Leixuri Aguirre, Alfredo Fernández-Quintela, Noemí Arias, Maria P. Portillo   +3 more
doaj   +1 more source

Ganoderma tsugae Inhibits the SREBP-1/AR Axis Leading to Suppression of Cell Growth and Activation of Apoptosis in Prostate Cancer Cells

Molecules, 2018
Recent research suggests that the activation of lipid biosynthesis (lipogenesis) is linked with prostate cancer (PCa) malignancy. Sterol regulatory element-binding protein-1 (SREBP-1) is a key transcriptional regulator controlling lipogenesis.
Shih-Yin Huang, Guan-Jhong Huang, Hsi-Chin Wu, Ming-Ching Kao, Wen-Chin Huang   +4 more
doaj   +1 more source

Changes in the sensitivity of lipogenesis in rat hepatocytes to hormones and precursors over the diurnal cycle and during longer-term starvation of donor animals.

Journal of Lipid Research, 1984
In rat hepatocytes freshly isolated from donor rats at different times of the day, the rates of lipogenesis (de novo fatty acid synthesis) varied with a diurnal periodicity.
G F Gibbons, C R Pullinger, O G Björnsson   +2 more
doaj  

Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor–mediated activation of hepatic lipogenesis-related genes

Poultry Science, 2020
In avian species, liver lipid metabolism plays an important role in egg laying performance. Previous studies indicate that betaine supplementation in laying hens improves egg production.
Nagmeldin A. Omer, Yun Hu, Abdulrahman A. Idriss, Halima Abobaker, Zhen Hou, Shu Yang, Wenqiang Ma, Ruqian Zhao   +7 more
doaj  

Potential of Traditional Medicinal Plants for Treating Obesity: A Review [PDF]

2012 International Conference on Nutrition and Food Sciences, IPCBEE vol. 39 (2012) IACSIT Press, Singapore, 2012
Obesity is a global health concern associated with high morbidity and mortality. Therapeutic strategies include synthetic drugs and surgery, which may entail high costs and serious complications. Plant-based medicinal agents offer an alternative approach.
arxiv  

Lipidomic approach for stratification of Acute Myeloid Leukemia patients [PDF]

arXiv, 2016
The pathogenesis and progression of many tumors, including hematologic malignancies is highly dependent on enhanced lipogenesis. De novo fatty-acid synthesis permits accelerated proliferation of tumor cells by providing structural components to build the membranes.
arxiv  

Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1 s⃞

Journal of Lipid Research, 2006
Lipogenic diets that are completely devoid of methionine and choline (MCD) induce hepatic steatosis. MCD feeding also provokes systemic weight loss, for unclear reasons.
Gizem Rizki, Lorenzo Arnaboldi, Bianca Gabrielli, Jim Yan, Gene S. Lee, Ray K. Ng, Scott M. Turner, Thomas M. Badger, Robert E. Pitas, Jacquelyn J. Maher   +9 more
doaj  

New device for preparing thin slices of adipose tissue for metabolic studies in vitro

Journal of Lipid Research, 1972
A new microtome is described which allows the rapid preparation of equal slices of well-defined thickness of fresh human tissue, especially adipose tissue.
J.-D. Faulhaber, H.-U. Klor, H. Ditschuneit   +2 more
doaj  

Apport lipidique et prise de poids

Oléagineux, Corps gras, Lipides, 2008
From a quantitative point of view the role of dietary fat in weight gain apparently seems clear, but its accountability in obesity pathogenesis, for individuals or population, is not definitively established. This concern may be divided in four sections.
Lecerf Jean-Michel
doaj   +1 more source