Results 71 to 80 of about 75,579 (341)

Oleic acid in Angus and Hanwoo (Korean native cattle) fat reduced the fatty acid synthase activity in rat adipose tissues

Journal of Animal Science and Technology, 2021
This study aimed to determine the blood lipid profiles, fatty acid composition, and lipogenic enzyme activities in rat adipose tissues as affected by the Angus beef fat (ABF) and Hanwoo beef fat (HBF) containing ...
Kim Margarette C. Nogoy, Hyoun Ju Kim, Dong Hoon Lee, Stephen B. Smith, Hyun A Seong, Seong Ho Choi   +5 more
doaj   +1 more source

Increased Lipogenesis is Critical for Self-Renewal and Growth of Breast Cancer Stem Cells: Impact of Omega-3 Fatty Acids [PDF]

, 2021
Haiqing Luo, Chih‐Yu Chen, Xiangyong Li, Xin Zhang, Chien‐Wen Su, Yinghua Liu, Tinglan Cao, Lei Hao, Meng Wang, Jing X. Kang   +9 more
openalex   +1 more source

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Standard of care for metastatic castration-resistant prostate cancer (mCRPC) mainly relies on suppression of androgen receptor (AR) signaling. This approach has no lasting benefit due to the emergence of resistance mechanisms, such as ligand-
G. Zadra, C. Ribeiro, Paolo Chetta, Y. Ho, Stefano Cacciatore, Xueliang Gao, Sudeepa Syamala, C. Bango, Cornelia Photopoulos, Ying Huang, S. Tyekucheva, D. Bastos, J. Tchaicha, Brian P. Lawney, T. Uo, Laura D’Anello, A. Csibi, R. Kalekar, B. Larimer, L. Ellis, L. Butler, C. Morrissey, Karen McGovern, V. Palombella, J. Kutok, U. Mahmood, S. Bosari, J. Adams, S. Peluso, S. Dehm, S. Plymate, M. Loda   +31 more
semanticscholar   +1 more source

GLS1‐RNA Polymerase II Axis Mediates Glutamine‐Dependent Hepatoprotective Effects on Alcoholic Liver Disease in High‐Protein Diets

Advanced Science, EarlyView.
GLS1 interacts with RNA polymerase II subunits, ROLR2H and POLR2E, resulting in significant suppression of RNA polymerase II activity. Importantly, the investigation demonstrates that high‐protein diets, particularly glutamine, exert protective effects against alcoholic fatty liver through GLS1‐RNA polymerase II axis.
Wenbiao Wu, Haowen Jiang, Yichang Liu, Chang Peng, Hanlin Wang, Wenhua Yang, Zan Lyu, Yan Sun, Huan Ma, Hongyu Gu, Weijuan Kan, Liya Jing, Tiancheng Dong, Chunmei Xia, Saifei Lei, Rui Wu, Jinlong Li, Jia Li   +17 more
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis [PDF]

, 2023
Mari C. Vázquez‐Borrego, Mercedes del Río-Moreno, Maxim Pyatkov, André Sarmento‐Cabral, Mariyah Mahmood, Natalie Pelke, Magdalena Wnek, José Córdoba‐Chacón, David J. Waxman, Michelle A. Puchowicz, Owen P. McGuinness, Rhonda D. Kineman   +11 more
openalex   +1 more source

Food Restriction and Lipogenesis in the Rat.

Experimental Biology and Medicine, 1964
Summary1. Using young male rats fed chow for only 2 hours daily, the increased lipogenesis in vitro and liver glycogen concentration reported by others has been confirmed. The phenomena have been demonstrated also in young male rats fed a purified, high carbohydrate diet for only 2 hours daily. 2.
John R. Beaton, J. A. F. Stevenson, V. Feleki, A. J. Szlavko   +3 more
openaire   +3 more sources

Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages

Advanced Science, EarlyView.
Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh, Albert Kallon Koroma, Rajeev Kumar Pandey, Yongfang Wang, Jinnan Cheng, Philipp Haas, Mahyar Aghapour, Linda Krug, Adelheid Hainzl, Meinhard Wlaschek, Pallab Maity, Karin Scharffetter‐Kochanek   +11 more
wiley   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Gypenoside XIII regulates lipid metabolism in HepG2 hepatocytes and ameliorates nonalcoholic steatohepatitis in mice

Kaohsiung Journal of Medical Sciences
Gypenoside XIII is isolated from Gynostemma pentaphyllum (Thunb.) Makino. In mice, G. pentaphyllum extract and gypenoside LXXV have been shown to improve non‐alcoholic steatohepatitis (NASH).
Shu‐Chen Cheng, Chian‐Jiun Liou, Ya‐Xuan Wu, Kuo‐Wei Yeh, Li‐Chen Chen, Wen‐Chung Huang   +5 more
doaj   +1 more source