Results 71 to 80 of about 16,244 (260)
In-silico and in-vitro analysis of Lipogenesis Effect of Shorea macrophylla Fruits’ Crude Extract [PDF]
, 2023 Lipogenesis is a mechanism that enhance lipid deposits in meat, and it can increase the market value of meat as increasing of its content in meat would improve meat quality.
Ivy Yee Yen, Chew
core
Advanced Science, EarlyView.SLC25A4high hepatocytes drive metabolic‐associated steatotic liver disease (MASLD) remission by recruiting lipid‐eating macrophages. The hepatocyte Slc25a4/PANX1/ATP/P2ry12 axis mediates find‐me signaling that triggers macrophage recruitment and efferocytosis, while recruited macrophages secrete GDF15 to activate hepatocyte PPARα and promote fatty acid
Yiting Qian +8 more
wiley +1 more source
Liver X Receptor: an oxysterol sensor and a major playerin the control of lipogenesis
, 2011 De novo fatty acid biosynthesis is also called lipogenesis. It is a metabolic pathway that provides the cellswith fatty acids required for major cellular processes such as energy storage, membrane structures andlipid signaling.
Ducheix, Simon +7 more
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Hedgehog signaling via Gli2 prevents obesity induced by high-fat diet in adult mice
eLife, 2017 Obesity poses a significant risk of developing type II diabetes and other diseases. Hedgehog (Hh) signaling has been shown to inhibit adipose tissue development, but its effect on diet-induced obesity during postnatal life is not known.
Yu Shi, Fanxin Long
doaj +1 more source
Pharmaceutics, 2023 Obesity, as a major cause of many chronic diseases such as diabetes, cardiovascular disease, and cancer, is among the most serious health problems. Increased monoamine oxidase (MAO) activity has been observed in the adipose tissue of obese humans and ...
Hye-Young Joung +4 more
doaj +1 more source
Hormonal Regulation of Lipogenesis
, 2013 Obesity has reached epidemic proportions with severe heath consequences including type 2 diabetes, nonalcoholic fatty liver disease, and premature cardiovascular mortality. Understanding the biological processes that govern fat deposition in a tissue-specific manner is therefore crucial if we are to try to design novel and efficacious treatments that ...
Gathercole, L, Morgan, SA, Tomlinson, J
openaire +2 more sources
Advanced Science, EarlyView.USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian +9 more
wiley +1 more source
Expression of STING in Women with Morbid Obesity and Nonalcoholic Fatty Liver Disease
Metabolites, 2023 Nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic hepatic disease. Although mostly benign, this disease can evolve into nonalcoholic steatohepatitis (NASH).
Laia Bertran +11 more
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Advanced Science, EarlyView.SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han +8 more
wiley +1 more source
Epigenetic Regulation of Hepatic Lipogenesis: Role in Hepatosteatosis and Diabetes [PDF]
, 2020 Hepatosteatosis, which is frequently associated with development of metabolic syndrome and insulin resistance, manifests when triglyceride (TG) input in the liver is greater than TG output, resulting in the excess accumulation of TG.
Viscarra, Jose, Sul, Hei Sook
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