Results 101 to 110 of about 152,191 (283)

Short-Chain Fatty Acids Differentially Affect Intracellular Lipolysis in a Human White Adipocyte Model

Frontiers in Endocrinology, 2018
Background and aims Gut-derived short-chain fatty acids (SCFA), formed by microbial fermentation of dietary fibers, are believed to be involved in the etiology of obesity and diabetes.
J. Jocken, Manuel A. González Hernández, Nicole T. H. Hoebers, C. M. van der Beek, Yvonne P. G. Essers, E. Blaak, E. Canfora   +6 more
semanticscholar   +1 more source

Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells - Activation of protein kinase B by wortmannin-sensitive and -insensittve mechanisms [PDF]

, 1997
Previous studies using L6 myotubes have suggested that glycogen synthase kinase-3 (GSK-3) is phosphoryl ated and inactivated in response to insulin by protein kinase B (PKB, also known as Akt or RAG) (Cross, D, A, E., Alessi, D, R., Cohen, P ...
Denton, Richard M., Edgell, Nigel J., Foulstone, Emily J., Moule, S. Kelly, Proud, Christopher G., Welsh, Gavin I.   +5 more
core  

Differential effects of dietary supplements on metabolomic profile of smokers versus non-smokers. [PDF]

, 2012
BackgroundCigarette smoking is well-known to associate with accelerated skin aging as well as cardiovascular disease and lung cancer, in large part due to oxidative stress.
Beebe, Kirk D, Chang, Anne Lynn S, Cheng, Michelle Y, Chun, Kimberly A, Gorell, Emily S, Kern, Dale G, Knaggs, Helen E, Munoz, Claudia A, Spitale, Robert C, Wood, Steve M, Wulff, Jacob   +10 more
core   +4 more sources

Cell-intrinsic lysosomal lipolysis is essential for macrophage alternative activation

Nature Immunology, 2014
Alternative (M2) activation of macrophages driven via the α-chain of the receptor for interleukin 4 (IL-4Rα) is important for immunity to parasites, wound healing, the prevention of atherosclerosis and metabolic homeostasis.
S. C. Huang, B. Everts, Yulia Ivanova, David O’Sullivan, Marcia Nascimento, A. Smith, W. Beatty, L. Love-Gregory, W. Lam, Christina M. O’Neill, Cong Yan, H. Du, N. Abumrad, J. Urban, M. Artyomov, Erika L. Pearce, Edward J. Pearce   +16 more
semanticscholar   +1 more source

Identification of lysosomal lipolysis as an essential noncanonical mediator of adipocyte fasting and cold-induced lipolysis

The Journal of Clinical Investigation
Adipose tissue lipolysis is the process by which triglycerides in lipid stores are hydrolyzed into free fatty acids (FFAs), serving as fuel during fasting or cold-induced thermogenesis.
Yu-Sheng Yeh, Trent D. Evans, Mari Iwase, Se-Jin Jeong, Xiangyu Zhang, Ziyang Liu, Arick Park, Ali Ghasemian, Borna Dianati, Ali Javaheri, Dagmar Kratky, Satoko Kawarasaki, Tsuyoshi Goto, Hanrui Zhang, Partha Dutta, Francisco J. Schopfer, Adam C. Straub, Jaehyung Cho, Irfan J. Lodhi, Babak Razani   +19 more
doaj   +1 more source

Performance of three commercial lipases in a model enzyme modified cheese system : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology in Food Technology at Massey University [PDF]

, 1999
The effects of Amano 'R' (from Penicillium roqueforti), Palatase (from Mucor miehei) and kid lipase (from kid goat) activity on hydrolysis of triglycerides in a constant enzyme modified cheese (EMC) base have been investigated.
Gunaratne, Jagath Thusitha Kumara
core  

Protein kinase CβI interacts with the β1-adrenergic signaling pathway to attenuate lipolysis in rat adipocytes [PDF]

, 2008
We have shown previously that insulin attenuates β1-adrenergic receptor (β1-AR)-mediated lipolysis viaactivation of protein kinase C (PKC) in rat adipocytes.
Nakamura Jiro, 中村 二郎
core   +1 more source

Modulation of lipolysis and glycolysis pathways in cancer stem cells changed multipotentiality and differentiation capacity toward endothelial lineage

Cell & Bioscience, 2019
Cancer stem cells obtain energy demand through the activation of glycolysis and lipolysis. It seems that the use of approached targeting glycolysis and lipolysis could be an effective strategy for the inhibition of cancer stem cells.
Ayda Pouyafar, Milad Zadi Heydarabad, Jalal Abdolalizadeh, Reza Rahbarghazi, Mehdi Talebi   +4 more
doaj   +1 more source

The pharmacology and function of receptors for short-chain fatty acids [PDF]

, 2015
Despite some blockbuster G protein–coupled receptor (GPCR) drugs, only a small fraction (∼15%) of the more than 390 nonodorant GPCRs have been successfully targeted by the pharmaceutical industry.
Bolognini, Daniele, Milligan, Graeme, Moss, Catherine E., Tobin, Andrew B.   +3 more
core   +1 more source

Conjugated linoleic acid and betaine affect lipolysis in pig adipose tissue explants

Animal, 2019
Consumers’ demand of leaner meat products is a challenge. Although betaine and conjugated linoleic acid (CLA) have the potential to decrease porcine adipose tissue, their mode of action is poorly understood.
I. Fernández-Fígares, M. Lachica, M. Martínez-Pérez, T.G. Ramsay   +3 more
doaj   +1 more source