Results 31 to 40 of about 144,905 (388)
Rapid orbital lipolysis associated with critical illness and colectomy
Orbital lipolysis typically develops in the setting of a chronic catabolic state. The acute development and rapid progression of orbital lipolysis are much less commonly described.
Joy Li, AB+6 more
doaj +1 more source
Glucagon stimulates gluconeogenesis by InsP3R-I mediated hepatic lipolysis
Although it is well-established that reductions in the ratio of insulin to glucagon in the portal vein have a major role in the dysregulation of hepatic glucose metabolism in type-2 diabetes 1 – 3 , the mechanisms by which glucagon affects hepatic ...
R. Perry+19 more
semanticscholar +1 more source
Glucocorticoid Receptor and Adipocyte Biology. [PDF]
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A+2 more
core +2 more sources
Antilipolytic actions of insulin on basal and hormone-induced lipolysis in rat adipocytes
The levels of insulin, free fatty acids (FFA), and triglycerides in rat sera increase with age. The increase in serum FFA levels accompanied the stimulation of basal lipolysis (i.e., lipolysis in the absence of lipolytic agents) in fat cells and ...
Chie Morimoto+2 more
doaj +1 more source
Regulation of Lipolysis in Adipocytes [PDF]
Lipolysis of white adipose tissue triacylglycerol stores results in the liberation of glycerol and nonesterified fatty acids that are released into the vasculature for use by other organs as energy substrates. In response to changes in nutritional state, lipolysis rates are precisely regulated through hormonal and biochemical signals.
Eszter Sarkadi-Nagy+4 more
openaire +3 more sources
A systems biology analysis of brain microvascular endothelial cell lipotoxicity. [PDF]
BackgroundNeurovascular inflammation is associated with a number of neurological diseases including vascular dementia and Alzheimer's disease, which are increasingly important causes of morbidity and mortality around the world.
Aung, Hnin H+3 more
core +2 more sources
During activation, T cells undergo metabolic reprogramming, which imprints distinct functional fates. We determined that on PD-1 ligation, activated T cells are unable to engage in glycolysis or amino acid metabolism but have an increased rate of fatty ...
N. Patsoukis+11 more
semanticscholar +1 more source
Docosahexaenoic acid (DHA) is a biologically active fatty acid that reduces the accumulation of lipids. However, the molecular mechanism underlying this process, particularly in fish, is not well understood. Recent studies show that endoplasmic reticulum
Xiaocheng Huang+4 more
doaj +1 more source
Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P.+10 more
core +1 more source
Lipid droplet size directs lipolysis and lipophagy catabolism in hepatocytes
Lipolysis and lipophagy are thought to be distinct mechanisms for lipid droplet catabolism. In hepatocytes, Schott et al. report that these pathways may operate synergistically: the lipolysis enzyme ATGL targets large LDs upstream of lipophagy, which is ...
Micah B. Schott+6 more
semanticscholar +1 more source