Results 41 to 50 of about 152,191 (283)

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A, Lee, Rebecca A, Wang, Jen-Chywan   +2 more
core   +2 more sources

Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in Mice. [PDF]

, 2017
Hypoadiponectinemia has been widely observed in patients with gestational diabetes mellitus (GDM). To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (Adipoq-/- ) and wild-type (WT) mice were crossed to produce ...
Hay, William W, Lee, Samuel, Nguyen, Amanda, Qiao, Liping, Schaack, Jerome, Shao, Jianhua, Wattez, Jean-Sebastien   +6 more
core   +1 more source

Suppression of adipose lipolysis by long-chain fatty acid analogs

Journal of Lipid Research, 2012
Agonist-induced lipolysis of adipose fat is robustly inhibited by insulin or by feedback inhibition by the long-chain fatty acids (LCFA) produced during lipolysis. However, the mode of action of LCFA in suppressing adipose lipolysis is not clear.
Bella Kalderon, Narmen Azazmeh, Nili Azulay, Noam Vissler, Michael Valitsky, Jacob Bar-Tana   +5 more
doaj   +1 more source

Effects of pre-exercise carbohydrate consumption on metabolism during exercise [PDF]

, 2016
It is well documented that consuming carbohydrates (CHO) prior to exercise has been shown to alter metabolism. There are many ways that CHO ingestion affects substrate utilization and blood glucose dynamics at the start of exercise.
Montzingo, Luke James
core   +1 more source

A systems biology analysis of brain microvascular endothelial cell lipotoxicity. [PDF]

, 2014
BackgroundNeurovascular inflammation is associated with a number of neurological diseases including vascular dementia and Alzheimer's disease, which are increasingly important causes of morbidity and mortality around the world.
Aung, Hnin H, Rutledge, John C, Tagkopoulos, Ilias, Tsoukalas, Athanasios   +3 more
core   +2 more sources

O-GlcNAc transferase inhibits visceral fat lipolysis and promotes diet-induced obesity

Nature Communications, 2020
Excessive visceral fat accumulation is a primary risk factor for metabolically unhealthy obesity and related diseases. The visceral fat is highly susceptible to the availability of external nutrients.
Yunfan Yang, Minnie Fu, Min-Dian Li, Kaisi Zhang, Bichen Zhang, Simeng Wang, Yuyang Liu, W. Ni, Qunxiang Ong, Jia Mi, Xiaoyong Yang   +10 more
semanticscholar   +1 more source

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]

, 2016
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P., Chen, Fen, Chen, Shi Y, Fu, Jian F, Shan, Yu J, Wang, An S, Yao, An J, Zhang, Hui Q, Zhang, Xiao H, Zhao, Jin S, Zhou, Zu Q   +10 more
core   +1 more source

RBP4 increases lipolysis in human adipocytes and is associated with increased lipolysis and hepatic insulin resistance in obese women

The FASEB Journal, 2020
Retinol‐binding protein‐4 (RBP4) is elevated in serum and adipose tissue (AT) in obesity‐induced insulin resistance and correlates inversely with insulin‐stimulated glucose disposal.
Murat Kilicarslan, B. D. de Weijer, Kotryna Simonyté Sjödin, Pratik Aryal, K. T. ter Horst, H. Cakir, J. Romijn, M. Ackermans, I. Janssen, F. Berends, Arnold van de Laar, A. Houdijk, B. Kahn, M. Serlie   +13 more
semanticscholar   +1 more source

Systemic Nanoparticle‐Mediated Delivery of Pantetheinase Vanin‐1 Regulates Lipolysis and Adiposity in Abdominal White Adipose Tissue

Advanced Science, 2020
Lipolysis in white adipose tissue (WAT) occurs in response to nutritional signals and helps to regulate lipid turnover/adiposity in animals. However, the causal relationships and the mechanisms controlling WAT morphology are not clear.
Siyu Chen, Wenxiang Zhang, Chen Sun, Mingming Song, Shuang Liu, Mengyi Xu, Xiaojin Zhang, Li Liu, Chang Liu   +8 more
doaj   +1 more source

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

Nature Communications, 2015
During activation, T cells undergo metabolic reprogramming, which imprints distinct functional fates. We determined that on PD-1 ligation, activated T cells are unable to engage in glycolysis or amino acid metabolism but have an increased rate of fatty ...
N. Patsoukis, Kankana Bardhan, Pranam Chatterjee, Duygu Sari, Bianling Liu, L. N. Bell, Edward D. Karoly, G. Freeman, V. Petkova, P. Seth, Lequn Li, V. Boussiotis   +11 more
semanticscholar   +1 more source